HitPredict

Interactor 1: FCG3B (O75015)
Low affinity immunoglobulin gamma Fc region receptor III-B (Fc-gamma RIII-beta) (CD16-I) (Fc-gamma RIII) (Fc-gamma RIIIb) (FcRIII) (FcRIIIb) (FcR-10) (IgG Fc receptor III-1) (CD antigen CD16b)
Gene: FCGR3B

Interactor 2: LRC8C (Q8TDW0)
Volume-regulated anion channel subunit LRRC8C (Factor for adipocyte differentiation 158) (Leucine-rich repeat-containing protein 8C)
Gene: LRRC8C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 233 Hs			1 803
+	Hs
		252748 FCG3B_HUMAN (1-233): 1.58e-56: 181: 100.00		LRC8E_HUMAN (491-803): 1.09e-30: 131: 19.94
+	Hs
		92673 E9PNY5_HUMAN (18-120): 5.65e-40: 134: 100.00		LRC8C_HUMAN (474-803): 2.36e-34: 142: 19.54
+	Hs
		92671 E9PNY5_HUMAN (18-120): 5.65e-40: 134: 100.00		LRC8E_HUMAN (491-803): 1.09e-30: 131: 19.94