HitPredict

Interactor 1: PLXA2 (O75051)
Plexin-A2 (Semaphorin receptor OCT)
Gene: PLXNA2

Interactor 2: DEF1 (P59665)
Neutrophil defensin 1 (Defensin, alpha 1) (HNP-1) (HP-1) (HP1) [Cleaved into: HP 1-56; Neutrophil defensin 2 (HNP-2) (HP-2) (HP2)]
Gene: DEFA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1894 Hs			1 94
+	Hs
		253461 PLXA2_HUMAN (1-1894): 0: 2664: 100.00		DEF5_HUMAN (1-94): 4.72e-33: 111: 48.94
+	Hs
		887073 PLXA1_HUMAN (8-1894): 0: 2455: 63.51		DEF1_HUMAN (1-94): 1.04e-44: 141: 100.00
+	Hs
		965269 PLXA1_HUMAN (8-1894): 0: 2455: 63.51		DEF5_HUMAN (1-94): 4.72e-33: 111: 48.94
+	Hs
		165176 PLXB2_HUMAN (36-1891): 0: 1941: 32.04		DEF1_HUMAN (1-94): 1.04e-44: 141: 100.00
+	Hs
		165191 PLXB2_HUMAN (36-1891): 0: 1941: 32.04		DEF5_HUMAN (1-94): 4.72e-33: 111: 48.94