Protein: CXCR2
C-X-C chemokine receptor type 2 (CXC-R2) (CXCR-2) (CDw128b) (GRO/MGSA receptor) (High affinity interleukin-8 receptor B) (IL-8R B) (IL-8 receptor type 2) (CD antigen CD182)

Gene: CXCR2
Organism: Homo sapiens
Interactions: 60
UniProt ID: P25025

Gene Ontology (top 5):
GO:0002407 - dendritic cell chemotaxis
GO:0004918 - interleukin-8 receptor activity
GO:0004930 - G protein-coupled receptor activity
GO:0005654 - nucleoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

486185

IL8
Interleukin-8

18

20

Small-scale

0.985

High

448988

GROA
Growth-regulated alpha protein

9

20

Small-scale

0.957

High

364042

CXCL7
Platelet basic protein

3

20

Small-scale

0.827

High

625744

CXCR2
C-X-C chemokine receptor type 2

2

18

Small-scale

0.776

High

625748

CXCL5
C-X-C motif chemokine 5

2

20

Small-scale

0.776

High

625762

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

17

Small-scale

0.665

High

625747

GRIA1
Glutamate receptor 1

3

7

Small-scale

0.640

High

587767

CXCL2
C-X-C motif chemokine 2

1

20

Small-scale

0.618

High

587786

CXCL3
C-X-C motif chemokine 3

1

20

Small-scale

0.618

High

625735

CXCR1
C-X-C chemokine receptor type 1

1

19

Small-scale

0.618

High

625750

ARRB1
Beta-arrestin-1

1

12

Small-scale

0.618

High

625758

CXCL6
C-X-C motif chemokine 6

1

20

Small-scale

0.618

High

625753

EMP1
Epithelial membrane protein 1

2

4

High-throughput

0.606

High

625760

VMAT2
Synaptic vesicular amine transporter

2

3

High-throughput

0.606

High

625763

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

2

1

High-throughput

0.606

High

625770

CLD22
Claudin-22

2

4

High-throughput

0.606

High

625775

TMM80
Transmembrane protein 80

2

1

High-throughput

0.606

High

625779

AT131
Endoplasmic reticulum transmembrane helix translocase

2

20

High-throughput

0.606

High

625780

S39A2
Zinc transporter ZIP2

2

6

High-throughput

0.606

High

625749

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

1

Small-scale

0.599

High

625777

TM147
BOS complex subunit TMEM147

2

0

High-throughput

0.580

High

625781

SMCO4
Single-pass membrane and coiled-coil domain-containing protein 4

2

0

High-throughput

0.580

High

625764

LASP1
LIM and SH3 domain protein 1

2

5

Small-scale

0.567

High

625754

TERA
Transitional endoplasmic reticulum ATPase

1

1

Small-scale

0.536

High

625755

1433G
14-3-3 protein gamma

1

8

Small-scale

0.536

High

625751

F10A1
Hsc70-interacting protein

1

3

Small-scale

0.535

High

380240

HG2A
HLA class II histocompatibility antigen gamma chain

1

3

Small-scale

0.515

High

625773

TF3A
Transcription factor IIIA

1

1

Small-scale

0.515

High

61011

A5PKU2
TUSC5 protein

1

7

High-throughput

0.515

High

169035

ARPC3
Actin-related protein 2/3 complex subunit 3

1

0

Small-scale

0.513

High

625752

VASP
Vasodilator-stimulated phosphoprotein

1

0

Small-scale

0.513

High

625769

TARG1
Trafficking regulator of GLUT4 1

1

7

High-throughput

0.481

High

535794

MIF
Macrophage migration inhibitory factor

1

0

Small-scale

0.480

High

625746

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

3

Small-scale

0.479

High

625768

RFIP2
Rab11 family-interacting protein 2

1

2

Small-scale

0.479

High

625774

TF3B
Transcription factor IIIB 90 kDa subunit

1

2

Small-scale

0.479

High

625757

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

0

Small-scale

0.458

High

625783

MYO5B
Unconventional myosin-Vb

1

0

Small-scale

0.458

High

168505

SCAM2
Secretory carrier-associated membrane protein 2

1

5

Small-scale

0.445

High

376166

ANXA1
Annexin A1

1

3

Small-scale

0.445

High

533193

PLSL
Plastin-2

1

6

Small-scale

0.445

High

625745

PSA2
Proteasome subunit alpha type-2

1

1

Small-scale

0.445

High

625756

1433Z
14-3-3 protein zeta/delta

1

8

Small-scale

0.445

High

625759

CLH1
Clathrin heavy chain 1

1

1

Small-scale

0.445

High

625761

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

1

Small-scale

0.445

High

625778

KLC2
Kinesin light chain 2

1

1

Small-scale

0.445

High

625784

TLN1
Talin-1

1

5

Small-scale

0.445

High

625766

GASP1
G-protein coupled receptor-associated sorting protein 1

1

5

Small-scale

0.437

High

625767

RN123
E3 ubiquitin-protein ligase RNF123

1

3

High-throughput

0.437

High

625771

DYH5
Dynein axonemal heavy chain 5

1

1

Small-scale

0.437

High

121682

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

0

Small-scale

0.426

High

168885

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

Small-scale

0.426

High

413832

GELS
Gelsolin

1

0

Small-scale

0.426

High

625765

LIN41
E3 ubiquitin-protein ligase TRIM71

1

1

Small-scale

0.407

High

625782

DYH17
Dynein axonemal heavy chain 17

1

1

Small-scale

0.407

High

625772

CD003
Uncharacterized protein C4orf3

2

0

High-throughput

0.316

High

625776

NIPS1
Protein NipSnap homolog 1

1

0

Small-scale

0.279

Low

131803

FAAH1
Fatty-acid amide hydrolase 1

1

0

Small-scale

0.249

Low

573133

TCPA
T-complex protein 1 subunit alpha

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024