Interactor 1: FZD7 (O75084)
Frizzled-7 (Fz-7) (hFz7) (FzE3)
Gene: FZD7

Interactor 2: FZD2 (Q14332)
Frizzled-2 (Fz-2) (hFz2) (FzE2)
Gene: FZD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Frizzled~Frizzled, Frizzled~Fz, Fz~Fz
Common GO terms GO:0004930 - G protein-coupled receptor activity
GO:0005886 - plasma membrane
GO:0017147 - Wnt-protein binding
GO:0030165 - PDZ domain binding
GO:0030182 - neuron differentiation
and 5 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 574
Hs

1 565
+ Rn
+ Rn
+ Rn
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm

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Last updated: 15 Jul 2024