HitPredict

Interactor 1: LIPA3 (O75145)
Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3)
Gene: PPFIA3

Interactor 2: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	9624153
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SAM_1~SAM_1, SAM_1~SAM_2, SAM_2~SAM_2
Common GO terms	GO:0005829 - cytosol GO:0048786 - presynaptic active zone GO:0050808 - synapse organization
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1194 Hs			1 1202
+	Hs
		255231 LIPA3_HUMAN (1-1194): 6.31e-178: 557: 100.00		LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82
+	Hs
		1025277 LIPA1_HUMAN (1-1194): 6.96e-129: 426: 57.54		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		259642 LIPA1_HUMAN (1-1194): 6.96e-129: 426: 57.54		LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82
+	Hs
		259634 LIPA2_HUMAN (1-1194): 1.21e-124: 416: 54.80		LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82
+	Hs
		1025318 LIPA1_HUMAN (1-1194): 6.96e-129: 426: 57.54		LIPB2_HUMAN (434-1149): 2.41e-95: 327: 18.61
+	Hs
		259651 LIPA2_HUMAN (1-1194): 1.21e-124: 416: 54.80		LIPB2_HUMAN (434-1149): 2.41e-95: 327: 18.61
+	Dm
		65319 A8DYM0_DROME (820-1158): 5.99e-98: 340: 33.81		A8DYM0_DROME (860-1122): 3.71e-105: 360: 42.21
+	Hs
		255230 LIPA3_HUMAN (1-1194): 6.31e-178: 557: 100.00		LIPA3_HUMAN (1-265): 3.37e-12: 73.2: 12.45
+	Hs
		255249 LIPA3_HUMAN (1-1194): 6.31e-178: 557: 100.00		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Dm
		114427 M9PCD4_DROME (1-1118): 3.24e-75: 274: 36.17		Q9VU88_DROME (604-1148): 6.76e-85: 292: 22.95
+	Hs
		1025311 LIPA1_HUMAN (1-1194): 6.96e-129: 426: 57.54		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		259650 LIPA2_HUMAN (1-1194): 1.21e-124: 416: 54.80		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Dm
		65321 A8DYM0_DROME (820-1158): 5.99e-98: 340: 33.81		M9PCD4_DROME (3-277): 4.35e-10: 66.3: 12.59
+	Hs
		1202993 LIPB2_HUMAN (368-1140): 1.98e-78: 279: 19.61		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Dm
		114416 M9PCD4_DROME (1-1118): 3.24e-75: 274: 36.17		M9PCD4_DROME (3-277): 4.35e-10: 66.3: 12.59