HitPredict

Interactor 1: OBSL1 (O75147)
Obscurin-like protein 1
Gene: OBSL1

Interactor 2: ALPK2 (Q86TB3)
Alpha-protein kinase 2 (EC 2.7.11.1) (Heart alpha-protein kinase)
Gene: ALPK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	I-set~I-set, Ig_3~I-set
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1896 Hs			1 2170
+	Hs
		255957 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		TITIN_HUMAN (1-215): 2.35e-10: 68.7: 15.14
+	Hs
		255370 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		OBSL1_HUMAN (5-105): 4.13e-10: 67.5: 22.86
+	Hs
		234601 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		ROBO1_HUMAN (3-291): 2.27e-32: 140: 10.56
+	Mm
		57586 TITIN_MOUSE (1808-1896): 1.95e-09: 65.5: 21.11		TRPM7_MOUSE (1821-2167): 1.48e-111: 398: 19.89
+	Hs
		1060193 MYPC3_HUMAN (3-809): 4.94e-60: 229: 12.18		MYPC3_HUMAN (2-186): 5.02e-14: 80.3: 15.87
+	Hs
		1336275 ROBO1_HUMAN (1620-1894): 2.35e-37: 156: 25.75		ROBO2_HUMAN (3-445): 7.28e-34: 145: 13.49
+	Hs
		1336269 ROBO2_HUMAN (1-509): 1.1e-36: 154: 16.40		ROBO2_HUMAN (3-445): 7.28e-34: 145: 13.49
+	Hs
		1060200 MYPC3_HUMAN (3-809): 4.94e-60: 229: 12.18		TITIN_HUMAN (1-215): 2.35e-10: 68.7: 15.14
+	Hs
		1378225 ROBO1_HUMAN (1620-1894): 2.35e-37: 156: 25.75		ROBO1_HUMAN (3-291): 2.27e-32: 140: 10.56
+	Hs
		852394 TITIN_HUMAN (513-729): 2.01e-09: 65.5: 10.96		MYOM1_HUMAN (4-105): 2.52e-29: 130: 33.33
+	Hs
		870000 TITIN_HUMAN (513-729): 2.01e-09: 65.5: 10.96		MYOM2_HUMAN (5-114): 2.74e-21: 104: 28.57
+	Hs
		962505 MYPC1_HUMAN (7-99): 4.98e-17: 90.1: 24.73		MYPC2_HUMAN (7-128): 8e-13: 76.4: 17.56
+	Mm
		1160364 Q6P6L5_MOUSE (10-99): 8.87e-17: 88.9: 24.44		MYLK_MOUSE (11-124): 1.39e-12: 75.6: 16.67
+	Hs
		962510 MYPC1_HUMAN (7-99): 4.98e-17: 90.1: 24.73		TITIN_HUMAN (1-215): 2.35e-10: 68.7: 15.14
+	Hs
		1053315 TITIN_HUMAN (513-729): 2.01e-09: 65.5: 10.96		MYPC2_HUMAN (7-128): 8e-13: 76.4: 17.56
+	Hs
		1137771 OBSCN_HUMAN (1359-1557): 1.25e-10: 69.3: 18.54		TITIN_HUMAN (1-215): 2.35e-10: 68.7: 15.14
+	Ce
		136802 UNC22_CAEEL (11-99): 1.27e-09: 65.8: 22.47		UNC89_CAEEL (1-214): 1e-09: 66.4: 14.87