Protein: EMC9
ER membrane protein complex subunit 9 (Protein FAM158A)

Gene: EMC9
Organism: Homo sapiens
Interactions: 170
UniProt ID: Q9Y3B6

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0045050 - protein insertion into ER membrane by stop-transfer membrane-anchor sequence
GO:0071816 - tail-anchored membrane protein insertion into ER membrane
GO:0072546 - EMC complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1136422

EMC2
ER membrane protein complex subunit 2

11

5

Small-scale

0.981

High

1326954

EMC5
ER membrane protein complex subunit 5

3

1

High-throughput

0.871

High

1446126

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

5

2

High-throughput

0.720

High

1453748

EMC3
ER membrane protein complex subunit 3

5

2

High-throughput

0.720

High

1205508

EMC4
ER membrane protein complex subunit 4

3

2

High-throughput

0.675

High

1330447

EMC1
ER membrane protein complex subunit 1

3

2

High-throughput

0.675

High

1217129

EMC10
ER membrane protein complex subunit 10

2

2

High-throughput

0.628

High

1415016

EMC6
ER membrane protein complex subunit 6

2

1

High-throughput

0.628

High

244035

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

1

High-throughput

0.536

High

295262

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

3

High-throughput

0.536

High

346541

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.536

High

460672

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

1

High-throughput

0.536

High

550535

PABP1
Polyadenylate-binding protein 1

1

2

High-throughput

0.536

High

576852

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

3

High-throughput

0.536

High

608799

DDX5
Probable ATP-dependent RNA helicase DDX5

1

1

High-throughput

0.536

High

658488

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.536

High

673984

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.536

High

684443

DDX6
Probable ATP-dependent RNA helicase DDX6

1

2

High-throughput

0.536

High

860422

RS9
Small ribosomal subunit protein uS4

1

1

High-throughput

0.536

High

926563

SYRC
Arginine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.536

High

940337

SYMC
Methionine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.536

High

967617

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.536

High

969532

RS8
Small ribosomal subunit protein eS8

1

1

High-throughput

0.536

High

970189

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.536

High

972802

RS23
Small ribosomal subunit protein uS12

1

1

High-throughput

0.536

High

973358

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.536

High

982019

RL23
Large ribosomal subunit protein uL14

1

1

High-throughput

0.536

High

984596

RL30
Large ribosomal subunit protein eL30

1

1

High-throughput

0.536

High

985085

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.536

High

985586

RL32
Large ribosomal subunit protein eL32

1

1

High-throughput

0.536

High

992117

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.536

High

1013902

RL24
Large ribosomal subunit protein eL24

1

1

High-throughput

0.536

High

1029052

TIAR
Nucleolysin TIAR

1

3

High-throughput

0.536

High

1047150

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

1

High-throughput

0.536

High

1062730

DHX9
ATP-dependent RNA helicase A

1

1

High-throughput

0.536

High

1089934

ILF3
Interleukin enhancer-binding factor 3

1

1

High-throughput

0.536

High

1102141

PABP4
Polyadenylate-binding protein 4

1

2

High-throughput

0.536

High

1118201

DX39B
Spliceosome RNA helicase DDX39B

1

3

High-throughput

0.536

High

1121762

SAFB2
Scaffold attachment factor B2

1

3

High-throughput

0.536

High

1121928

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

2

High-throughput

0.536

High

1139702

SYK
Lysine--tRNA ligase

1

3

High-throughput

0.536

High

1198228

PDCD4
Programmed cell death protein 4

1

1

High-throughput

0.536

High

1287846

PABP2
Polyadenylate-binding protein 2

1

3

High-throughput

0.536

High

1288828

KTN1
Kinectin

1

2

High-throughput

0.536

High

1290198

THOC4
THO complex subunit 4

1

3

High-throughput

0.536

High

1369430

DDX17
Probable ATP-dependent RNA helicase DDX17

1

1

High-throughput

0.536

High

1382255

CCD47
PAT complex subunit CCDC47

1

1

High-throughput

0.536

High

1407967

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.536

High

1490509

PLAP
Phospholipase A-2-activating protein

1

1

High-throughput

0.536

High

161269

EI24
Etoposide-induced protein 2.4 homolog

1

0

High-throughput

0.513

High

300255

GLRX3
Glutaredoxin-3

1

0

High-throughput

0.513

High

359768

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.513

High

428254

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.513

High

428557

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.513

High

429072

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

447608

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

476881

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.513

High

583035

EZRI
Ezrin

1

0

High-throughput

0.513

High

586964

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

612022

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

612834

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.513

High

616062

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.513

High

627741

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.513

High

717006

RL12
Large ribosomal subunit protein uL11

1

0

High-throughput

0.513

High

749171

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.513

High

770337

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.513

High

773095

MYH9
Myosin-9

1

0

High-throughput

0.513

High

785550

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.513

High

809931

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.513

High

810473

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.513

High

824436

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.513

High

859123

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

859515

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

859735

RL21
Large ribosomal subunit protein eL21

1

0

High-throughput

0.513

High

860063

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.513

High

860650

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

868616

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.513

High

880408

RL34
Large ribosomal subunit protein eL34

1

0

High-throughput

0.513

High

895981

F10A1
Hsc70-interacting protein

1

0

High-throughput

0.513

High

898899

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.513

High

905519

HCFC1
Host cell factor 1

1

0

High-throughput

0.513

High

954322

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.513

High

960955

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.513

High

961446

RL27
Large ribosomal subunit protein eL27

1

0

High-throughput

0.513

High

961899

RL37A
Large ribosomal subunit protein eL43

1

0

High-throughput

0.513

High

965949

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

0

High-throughput

0.513

High

969733

RS15A
Small ribosomal subunit protein uS8

1

0

High-throughput

0.513

High

973005

RS18
Small ribosomal subunit protein uS13

1

0

High-throughput

0.513

High

976045

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.513

High

978798

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.513

High

979366

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.513

High

982888

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.513

High

983093

RS25
Small ribosomal subunit protein eS25

1

0

High-throughput

0.513

High

983365

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.513

High

985393

RL10A
Large ribosomal subunit protein uL1

1

0

High-throughput

0.513

High

986291

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.513

High

993042

RACK1
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.513

High

1016305

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

1024952

VIGLN
Vigilin

1

0

High-throughput

0.513

High

1037700

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.513

High

1057973

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.513

High

1117170

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.513

High

1454644

SYLC
Leucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.513

High

1462084

PRP19
Pre-mRNA-processing factor 19

1

0

High-throughput

0.513

High

1491140

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.513

High

1491142

YTHD2
YTH domain-containing family protein 2

1

0

High-throughput

0.513

High

81744

EIFCL
Eukaryotic translation initiation factor 3 subunit C-like protein

1

1

High-throughput

0.489

High

211085

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

1

High-throughput

0.489

High

255894

USO1
General vesicular transport factor p115

1

1

High-throughput

0.489

High

317047

MTA2
Metastasis-associated protein MTA2

1

1

High-throughput

0.489

High

462724

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

1

High-throughput

0.489

High

558515

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.489

High

559551

XRCC5
X-ray repair cross-complementing protein 5

1

1

High-throughput

0.489

High

698395

MAP4
Microtubule-associated protein 4

1

1

High-throughput

0.489

High

794677

RBMX
RNA-binding motif protein, X chromosome

1

4

High-throughput

0.489

High

846542

MATR3
Matrin-3

1

1

High-throughput

0.489

High

910745

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

3

High-throughput

0.489

High

939470

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

1

High-throughput

0.489

High

1089370

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

1

1

High-throughput

0.489

High

1093609

TRDN
Triadin

1

1

High-throughput

0.489

High

1134775

NUMA1
Nuclear mitotic apparatus protein 1

1

1

High-throughput

0.489

High

1368313

STAM1
Signal transducing adapter molecule 1

1

2

High-throughput

0.489

High

1405789

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

1

High-throughput

0.489

High

1491141

PRC2C
Protein PRRC2C

1

1

High-throughput

0.489

High

48849

ESYT2
Extended synaptotagmin-2

1

2

High-throughput

0.479

High

636037

PRPS3
Ribose-phosphate pyrophosphokinase 3

1

1

High-throughput

0.479

High

686539

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.479

High

837916

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

2

High-throughput

0.479

High

960039

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.479

High

985965

RL11
Large ribosomal subunit protein uL5

1

2

High-throughput

0.479

High

1039465

RL6
Large ribosomal subunit protein eL6

1

1

High-throughput

0.479

High

1334634

RN149
E3 ubiquitin-protein ligase RNF149

1

3

High-throughput

0.479

High

1431299

DJC25
DnaJ homolog subfamily C member 25

1

2

High-throughput

0.479

High

1450148

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.479

High

954646

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.445

High

218995

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

984669

RL39
Large ribosomal subunit protein eL39

1

1

High-throughput

0.437

High

1331383

ENAH
Protein enabled homolog

1

3

High-throughput

0.437

High

1448185

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.437

High

362

A0A075B6E5
ENAH actin regulator

1

1

High-throughput

0.407

High

94444

D6RAT0
Small ribosomal subunit protein eS1

1

1

High-throughput

0.407

High

107281

F8VR69
Ribosomal protein L6

1

1

High-throughput

0.407

High

116406

H3BUK8
Large ribosomal subunit protein eL13

1

1

High-throughput

0.407

High

837424

LAP2A
Lamina-associated polypeptide 2, isoform alpha

1

2

High-throughput

0.407

High

1202589

R39L5
Putative ribosomal protein eL39-like 5

1

1

High-throughput

0.407

High

1218551

Q5VVC8
Large ribosomal subunit protein uL5

1

2

High-throughput

0.407

High

1236389

MFSD5
Molybdate-anion transporter

1

1

High-throughput

0.407

High

250025

OGA
Protein O-GlcNAcase

2

0

High-throughput

0.328

High

1127643

SCN5A
Sodium channel protein type 5 subunit alpha

2

0

High-throughput

0.316

High

188068

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

0

High-throughput

0.279

Low

295374

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

High-throughput

0.279

Low

303667

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.279

Low

321702

PRP6
Pre-mRNA-processing factor 6

1

0

High-throughput

0.279

Low

694083

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.279

Low

973854

RUXE
Small nuclear ribonucleoprotein E

1

0

High-throughput

0.279

Low

975528

PRS10
26S proteasome regulatory subunit 10B

1

0

High-throughput

0.279

Low

977424

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.279

Low

1027871

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.279

Low

1130229

SMC1A
Structural maintenance of chromosomes protein 1A

1

0

High-throughput

0.279

Low

1203641

ZN326
DBIRD complex subunit ZNF326

1

0

High-throughput

0.279

Low

1206928

TOIP1
Torsin-1A-interacting protein 1

1

0

High-throughput

0.279

Low

1210559

HP1B3
Heterochromatin protein 1-binding protein 3

1

0

High-throughput

0.279

Low

1232745

H2A2A
Histone H2A type 2-A

1

0

High-throughput

0.279

Low

1361043

P66B
Transcriptional repressor p66-beta

1

0

High-throughput

0.279

Low

1415580

GNL3
Guanine nucleotide-binding protein-like 3

1

0

High-throughput

0.279

Low

1458625

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

High-throughput

0.279

Low

1460926

ZPI
Protein Z-dependent protease inhibitor

1

0

High-throughput

0.279

Low

1461315

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.279

Low

1490507

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.279

Low

1286966

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025