HitPredict

Interactor 1: H2B1K (O60814)
Histone H2B type 1-K (H2B K) (HIRA-interacting protein 1)
Gene: H2BC12

Interactor 2: IF4A3 (P38919)
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]
Gene: EIF4A3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 411
+	Sc
		381518 H2B2_YEAST (3-125): 7.28e-37: 123: 70.73		DHH1_YEAST (39-408): 1.29e-169: 486: 40.54
+	Hs
		659869 H2B1O_HUMAN (1-126): 2.89e-54: 167: 97.62		IF4A3_HUMAN (1-411): 1.51e-142: 413: 100.00
+	Hs
		807354 H2B1C_HUMAN (1-126): 1.08e-53: 166: 99.21		IF4A3_HUMAN (1-411): 1.51e-142: 413: 100.00
+	Hs
		807519 H2B1H_HUMAN (1-126): 5.45e-54: 166: 98.41		IF4A3_HUMAN (1-411): 1.51e-142: 413: 100.00
+	Hs
		754746 H2B1B_HUMAN (1-126): 1.53e-53: 165: 96.83		IF4A3_HUMAN (1-411): 1.51e-142: 413: 100.00