Protein: H2B1O
Histone H2B type 1-O (H2B-clustered histone 17) (Histone H2B.2) (Histone H2B.n) (H2B/n)

Gene: H2B1O, H2BC17
Organism: Homo sapiens
Interactions: 138
UniProt ID: P23527

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

591479

H2AX
Histone H2AX

5

20

High-throughput

0.922

High

418838

H2A1B
Histone H2A type 1-B/E

5

20

High-throughput

0.906

High

659883

H4
Histone H4

5

20

High-throughput

0.906

High

502241

H2A1
Histone H2A type 1

3

20

High-throughput

0.847

High

256772

H2B1K
Histone H2B type 1-K

3

20

High-throughput

0.827

High

659887

H31
Histone H3.1

3

20

High-throughput

0.827

High

501914

H2AZ
Histone H2A.Z

2

20

High-throughput

0.789

High

659896

H2A2C
Histone H2A type 2-C

2

20

High-throughput

0.789

High

659941

H2AJ
Histone H2A.J

2

20

High-throughput

0.789

High

507083

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

20

High-throughput

0.754

High

633998

H2A1D
Histone H2A type 1-D

2

20

High-throughput

0.754

High

659866

H2B1B
Histone H2B type 1-B

2

20

High-throughput

0.754

High

659879

H2B1D
Histone H2B type 1-D

2

20

High-throughput

0.754

High

659884

H2B1C
Histone H2B type 1-C/E/F/G/I

2

20

High-throughput

0.754

High

659903

H2A2A
Histone H2A type 2-A

2

20

High-throughput

0.754

High

659927

H2A1C
Histone H2A type 1-C

2

20

High-throughput

0.754

High

659928

H2B1H
Histone H2B type 1-H

2

20

High-throughput

0.754

High

659936

H2B1N
Histone H2B type 1-N

2

20

High-throughput

0.754

High

659939

H2B1L
Histone H2B type 1-L

2

20

High-throughput

0.754

High

659918

SIR6
NAD-dependent protein deacylase sirtuin-6

1

9

High-throughput

0.691

High

659891

XPC
DNA repair protein complementing XP-C cells

2

6

High-throughput

0.628

High

659948

E41L5
Band 4.1-like protein 5

2

1

High-throughput

0.628

High

231105

AIRE
Autoimmune regulator

1

20

Small-scale

0.618

High

277560

H2AY
Core histone macro-H2A.1

1

20

High-throughput

0.618

High

331962

KAT7
Histone acetyltransferase KAT7

1

20

High-throughput

0.618

High

342107

BRD1
Bromodomain-containing protein 1

1

20

High-throughput

0.618

High

449679

H2B1J
Histone H2B type 1-J

1

20

High-throughput

0.618

High

507537

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

20

High-throughput

0.618

High

521545

H14
Histone H1.4

1

20

High-throughput

0.618

High

595944

H12
Histone H1.2

1

20

High-throughput

0.618

High

659860

H2B1O
Histone H2B type 1-O

1

20

High-throughput

0.618

High

659872

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.618

High

659873

MCM2
DNA replication licensing factor MCM2

1

20

High-throughput

0.618

High

659876

BRPF1
Peregrin

1

20

High-throughput

0.618

High

659877

H2BFS
Histone H2B type F-S

1

20

High-throughput

0.618

High

659881

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

7

High-throughput

0.618

High

659885

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

20

High-throughput

0.618

High

659886

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

20

High-throughput

0.618

High

659889

H33
Histone H3.3

1

20

High-throughput

0.618

High

659897

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.618

High

659900

H2B2F
Histone H2B type 2-F

1

20

High-throughput

0.618

High

659907

H32
Histone H3.2

1

20

High-throughput

0.618

High

659908

H2AV
Histone H2A.V

1

20

High-throughput

0.618

High

659911

H2A3
Histone H2A type 3

1

20

High-throughput

0.618

High

659914

H2A2B
Histone H2A type 2-B

1

20

High-throughput

0.618

High

659915

H2B3B
Histone H2B type 3-B

1

20

High-throughput

0.618

High

659922

KAT6B
Histone acetyltransferase KAT6B

1

20

High-throughput

0.618

High

659926

KAT6A
Histone acetyltransferase KAT6A

1

20

High-throughput

0.618

High

659930

H2B1A
Histone H2B type 1-A

1

20

High-throughput

0.618

High

659932

H2A1H
Histone H2A type 1-H

1

20

High-throughput

0.618

High

659933

IPO9
Importin-9

1

15

High-throughput

0.618

High

659934

H2A1A
Histone H2A type 1-A

1

20

High-throughput

0.618

High

659937

H2A1J
Histone H2A type 1-J

1

20

High-throughput

0.618

High

659938

H2B1M
Histone H2B type 1-M

1

20

High-throughput

0.618

High

659946

WDR76
WD repeat-containing protein 76

1

18

High-throughput

0.618

High

659955

BRPF3
Bromodomain and PHD finger-containing protein 3

1

20

High-throughput

0.618

High

426445

HMGN2
Non-histone chromosomal protein HMG-17

2

20

High-throughput

0.584

High

601563

HMGA1
High mobility group protein HMG-I/HMG-Y

2

15

High-throughput

0.584

High

659861

IF4B
Eukaryotic translation initiation factor 4B

2

13

High-throughput

0.584

High

659874

KS6A3
Ribosomal protein S6 kinase alpha-3

2

20

High-throughput

0.571

High

659961

PCDBC
Protocadherin beta-12

2

20

High-throughput

0.553

High

659929

IGSF8
Immunoglobulin superfamily member 8

1

20

High-throughput

0.553

High

256582

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

3

High-throughput

0.536

High

286875

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

16

High-throughput

0.536

High

659865

ARRB2
Beta-arrestin-2

1

1

High-throughput

0.536

High

659871

ARRB1
Beta-arrestin-1

1

1

High-throughput

0.536

High

659882

RL7A
Large ribosomal subunit protein eL8

1

4

High-throughput

0.536

High

659909

H1FNT
Testis-specific H1 histone

1

5

High-throughput

0.536

High

659942

AN32E
Acidic leucine-rich nuclear phosphoprotein 32 family member E

1

8

High-throughput

0.536

High

659954

ZN346
Zinc finger protein 346

1

3

High-throughput

0.536

High

659957

ING4
Inhibitor of growth protein 4

1

16

High-throughput

0.536

High

659920

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.513

High

659894

FGFP1
Fibroblast growth factor-binding protein 1

1

2

High-throughput

0.489

High

659913

CACL1
CDK2-associated and cullin domain-containing protein 1

1

11

High-throughput

0.489

High

137419

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

1

20

High-throughput

0.479

High

137963

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

13

High-throughput

0.479

High

190820

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

20

High-throughput

0.479

High

286759

SKAP2
Src kinase-associated phosphoprotein 2

1

6

High-throughput

0.479

High

297459

PIAS1
E3 SUMO-protein ligase PIAS1

1

5

High-throughput

0.479

High

324538

HEXI1
Protein HEXIM1

1

14

High-throughput

0.479

High

486962

PARP1
Poly [ADP-ribose] polymerase 1

1

20

High-throughput

0.479

High

542335

TOP2A
DNA topoisomerase 2-alpha

1

15

High-throughput

0.479

High

571652

HCLS1
Hematopoietic lineage cell-specific protein

1

20

High-throughput

0.479

High

629566

BTF3
Transcription factor BTF3

1

11

High-throughput

0.479

High

659863

AKT1
RAC-alpha serine/threonine-protein kinase

1

20

High-throughput

0.479

High

659864

AKT2
RAC-beta serine/threonine-protein kinase

1

20

High-throughput

0.479

High

659867

MCM5
DNA replication licensing factor MCM5

1

20

High-throughput

0.479

High

659868

CYLC1
Cylicin-1

1

20

High-throughput

0.479

High

659869

IF4A3
Eukaryotic initiation factor 4A-III

1

5

High-throughput

0.479

High

659870

MAP1B
Microtubule-associated protein 1B

1

20

High-throughput

0.479

High

659875

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

17

High-throughput

0.479

High

659880

CD81
CD81 antigen

1

11

High-throughput

0.479

High

659888

RED1
Double-stranded RNA-specific editase 1

1

14

High-throughput

0.479

High

659890

MYPC1
Myosin-binding protein C, slow-type

1

16

High-throughput

0.479

High

659895

HMGN3
High mobility group nucleosome-binding domain-containing protein 3

1

14

High-throughput

0.479

High

659899

LARP7
La-related protein 7

1

20

High-throughput

0.479

High

659901

TEX35
Testis-expressed protein 35

1

12

High-throughput

0.479

High

659902

SMBT2
Scm-like with four MBT domains protein 2

1

20

High-throughput

0.479

High

659904

JADE1
Protein Jade-1

1

20

High-throughput

0.479

High

659910

MEPCE
7SK snRNA methylphosphate capping enzyme

1

14

High-throughput

0.479

High

659912

DPPA2
Developmental pluripotency-associated protein 2

1

10

High-throughput

0.479

High

659917

SYNPO
Synaptopodin

1

20

High-throughput

0.479

High

659921

SERB1
SERPINE1 mRNA-binding protein 1

1

12

High-throughput

0.479

High

659923

TITIN
Titin

1

19

High-throughput

0.479

High

659924

JADE3
Protein Jade-3

1

20

High-throughput

0.479

High

659925

ESR2
Estrogen receptor beta

1

10

High-throughput

0.479

High

659940

RIOK1
Serine/threonine-protein kinase RIO1

1

12

High-throughput

0.479

High

659943

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

20

High-throughput

0.479

High

659944

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.479

High

659947

EAF6
Chromatin modification-related protein MEAF6

1

4

High-throughput

0.479

High

659949

JADE2
E3 ubiquitin-protein ligase Jade-2

1

20

High-throughput

0.479

High

659950

DUOX2
Dual oxidase 2

1

12

High-throughput

0.479

High

659951

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

20

High-throughput

0.479

High

659953

PARP4
Protein mono-ADP-ribosyltransferase PARP4

1

18

High-throughput

0.479

High

659960

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

659862

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

659959

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

221528

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

5

High-throughput

0.437

High

369834

CO3
Complement C3

1

3

High-throughput

0.437

High

405596

HRG
Histidine-rich glycoprotein

1

14

High-throughput

0.437

High

427806

ICAM1
Intercellular adhesion molecule 1

1

20

High-throughput

0.437

High

659878

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

1

9

High-throughput

0.437

High

659892

GOGA2
Golgin subfamily A member 2

1

20

High-throughput

0.437

High

659893

CD5R2
Cyclin-dependent kinase 5 activator 2

1

12

High-throughput

0.437

High

659898

KNOP1
Lysine-rich nucleolar protein 1

1

8

High-throughput

0.437

High

659905

ZN474
Zinc finger protein 474

1

10

High-throughput

0.437

High

659906

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.437

High

659916

RHG24
Rho GTPase-activating protein 24

1

15

High-throughput

0.437

High

659919

FA47B
Protein FAM47B

1

20

High-throughput

0.437

High

659931

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.437

High

659935

MA7D2
MAP7 domain-containing protein 2

1

20

High-throughput

0.437

High

659945

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

659952

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

4

High-throughput

0.437

High

659958

TENN
Tenascin-N

1

20

High-throughput

0.437

High

659962

PCLO
Protein piccolo

1

20

High-throughput

0.437

High

297148

PRAF3
PRA1 family protein 3

1

0

High-throughput

0.279

Low

659956

LORF1
LINE-1 retrotransposable element ORF1 protein

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025