HitPredict

Interactor 1: SIN3B (O75182)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B

Interactor 2: BPTF (Q12830)
Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen)
Gene: BPTF

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1162 Hs			1 3046
+	Hs
		257851 SIN3B_HUMAN (1-1162): 0: 1453: 100.00		ZMYD8_HUMAN (2811-3032): 9.21e-40: 165: 24.61
+	Hs
		257774 SIN3B_HUMAN (1-1162): 0: 1453: 100.00		CHD3_HUMAN (356-439): 2.17e-18: 95.6: 33.33
+	Hs
		257822 SIN3B_HUMAN (1-1162): 0: 1453: 100.00		CIC_HUMAN (1024-2323): 3.62e-09: 65.2: 8.69
+	Hs
		1017340 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		BPTF_HUMAN (1-3046): 0: 1372: 100.00
+	Sc
		609137 SIN3_YEAST (38-241): 6.57e-30: 131: 28.08		GCN5_YEAST (2887-3033): 4.12e-45: 173: 32.65
+	Hs
		1018652 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		CHD3_HUMAN (356-439): 2.17e-18: 95.6: 33.33
+	Hs
		244825 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		BRD4_HUMAN (2936-3028): 1.03e-10: 70.1: 41.05
+	Hs
		1300903 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		CIC_HUMAN (1024-2323): 3.62e-09: 65.2: 8.69