Interactor 1: SIN3B (O75182)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.703

The method score is based on:

Property Details
Experiments 24981860, 15935060, 21258344, 26949739, 16464847
Identification Methods affinity chromatography technology, cross-linking study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1162
Hs

1 488
+ Hs
+ Mm
+ Mm
+ At
+ At
+ Hs
+ Mm
+ Dm
+ Dm
+ Ce
+ Ce
+ Mm
+ Hs
+ Sc
+ Sp
+ Sp
+ Sc
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024