HitPredict

Interactor 1: DNJA2 (O60884)
DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14)
Gene: DNAJA2

Interactor 2: HSP76 (P17066)
Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Gene: HSPA6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	21231916
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0042026 - protein refolding GO:0051082 - unfolded protein binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 643
+	Hs
		258781 DNJA2_HUMAN (1-412): 1.15e-169: 483: 100.00		HS71L_HUMAN (1-643): 0: 959: 79.32
+	Hs
		258741 DNJA2_HUMAN (1-412): 1.15e-169: 483: 100.00		HSP7C_HUMAN (4-615): 0: 937: 79.25
+	Hs
		600745 DNJA1_HUMAN (4-410): 1.4e-154: 444: 54.77		HSP76_HUMAN (1-643): 0: 970: 100.00
+	Hs
		600877 DNJA4_HUMAN (4-410): 2.26e-152: 438: 52.93		HSP76_HUMAN (1-643): 0: 970: 100.00
+	Hs
		258819 DNJA2_HUMAN (1-412): 1.15e-169: 483: 100.00		HSP72_HUMAN (3-643): 0: 923: 77.45
+	Hs
		727694 DNJA1_HUMAN (4-410): 1.4e-154: 444: 54.77		HS71L_HUMAN (1-643): 0: 959: 79.32
+	Hs
		536593 DNJA1_HUMAN (4-410): 1.4e-154: 444: 54.77		HSP7C_HUMAN (4-615): 0: 937: 79.25
+	Hs
		516182 DNJA1_HUMAN (4-410): 1.4e-154: 444: 54.77		HS71B_HUMAN (5-643): 0: 933: 82.16
+	Hs
		727740 DNJA1_HUMAN (4-410): 1.4e-154: 444: 54.77		HSP72_HUMAN (3-643): 0: 923: 77.45
+	Sc
		481502 MAS5_YEAST (4-412): 1.02e-144: 419: 46.73		HSP73_YEAST (8-643): 0: 911: 70.59
+	Sp
		267988 MAS5_SCHPO (4-412): 1.92e-142: 413: 46.49		HSP71_SCHPO (7-643): 0: 910: 69.78
+	Sp
		237852 MAS5_SCHPO (4-412): 1.92e-142: 413: 46.49		HSP72_SCHPO (8-613): 0: 907: 73.60
+	Hs
		600953 DNJB4_HUMAN (6-358): 1.21e-116: 345: 33.05		HSP76_HUMAN (1-643): 0: 970: 100.00
+	Hs
		761483 DNJA3_HUMAN (2-395): 1.68e-118: 355: 26.96		HS71L_HUMAN (1-643): 0: 959: 79.32
+	Hs
		761530 DNJB4_HUMAN (6-358): 1.21e-116: 345: 33.05		HS71L_HUMAN (1-643): 0: 959: 79.32
+	Ce
		233906 O45502_CAEEL (4-411): 3.27e-128: 377: 45.97		HSP1_CAEEL (4-643): 0: 921: 77.07
+	Hs
		537696 DNJA3_HUMAN (2-395): 1.68e-118: 355: 26.96		HSP7C_HUMAN (4-615): 0: 937: 79.25
+	Hs
		538056 DNJB4_HUMAN (6-358): 1.21e-116: 345: 33.05		HSP7C_HUMAN (4-615): 0: 937: 79.25
+	Hs
		516217 DNJB4_HUMAN (6-358): 1.21e-116: 345: 33.05		HS71B_HUMAN (5-643): 0: 933: 82.16
+	Hs
		931054 DNJA3_HUMAN (2-395): 1.68e-118: 355: 26.96		HSP72_HUMAN (3-643): 0: 923: 77.45