Protein: DNJB4
DnaJ homolog subfamily B member 4 (Heat shock 40 kDa protein 1 homolog) (HSP40 homolog) (Heat shock protein 40 homolog) (Human liver DnaJ-like protein)

Gene: DNJB4, DNAJB4
Organism: Homo sapiens
Interactions: 150
UniProt ID: Q9UDY4

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001671 - ATPase activator activity
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

679276

DNJB1
DnaJ homolog subfamily B member 1

7

12

High-throughput

0.963

High

298969

DNJB5
DnaJ homolog subfamily B member 5

6

12

High-throughput

0.945

High

538056

HSP7C
Heat shock cognate 71 kDa protein

5

20

High-throughput

0.912

High

1365257

HS105
Heat shock protein 105 kDa

4

20

High-throughput

0.896

High

761530

HS71L
Heat shock 70 kDa protein 1-like

2

20

High-throughput

0.789

High

761913

HSP74
Heat shock 70 kDa protein 4

2

20

High-throughput

0.789

High

600953

HSP76
Heat shock 70 kDa protein 6

2

20

Small-scale

0.757

High

1122705

TTL12
Tubulin--tyrosine ligase-like protein 12

5

4

High-throughput

0.712

High

535636

BIP
Endoplasmic reticulum chaperone BiP

1

20

High-throughput

0.691

High

1361253

DNJC9
DnaJ homolog subfamily C member 9

1

17

High-throughput

0.691

High

1405896

DNJC7
DnaJ homolog subfamily C member 7

1

19

High-throughput

0.691

High

1458947

NUDC
Nuclear migration protein nudC

1

4

High-throughput

0.691

High

194480

P2RX6
P2X purinoceptor 6

4

1

High-throughput

0.691

High

1458944

BAG5
BAG family molecular chaperone regulator 5

4

12

High-throughput

0.683

High

347388

BAG2
BAG family molecular chaperone regulator 2

3

8

High-throughput

0.650

High

176374

SYNEM
Synemin

4

3

High-throughput

0.633

High

1043873

KCNC4
Voltage-gated potassium channel KCNC4

2

4

High-throughput

0.628

High

1410249

TBL1Y
F-box-like/WD repeat-containing protein TBL1Y

2

11

High-throughput

0.628

High

130273

PGRC1
Membrane-associated progesterone receptor component 1

1

2

High-throughput

0.618

High

274793

DNJB6
DnaJ homolog subfamily B member 6

1

15

High-throughput

0.618

High

931146

HSP72
Heat shock-related 70 kDa protein 2

1

20

High-throughput

0.618

High

1407251

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

10

High-throughput

0.618

High

1458942

NRBP
Nuclear receptor-binding protein

1

1

High-throughput

0.618

High

351291

TTLL1
Polyglutamylase complex subunit TTLL1

3

4

High-throughput

0.609

High

1205760

CC038
Uncharacterized protein C3orf38

3

1

High-throughput

0.609

High

1356483

TB22A
TBC1 domain family member 22A

3

4

High-throughput

0.609

High

1458946

RUVB2
RuvB-like 2

2

3

High-throughput

0.606

High

1199955

P5CR3
Pyrroline-5-carboxylate reductase 3

2

2

High-throughput

0.601

High

1407008

NPAS1
Neuronal PAS domain-containing protein 1

2

9

High-throughput

0.601

High

1458952

KCNE3
Potassium voltage-gated channel subfamily E member 3

2

1

High-throughput

0.601

High

593710

BGAL
Beta-galactosidase

3

2

High-throughput

0.593

High

1454832

WRP73
WD repeat-containing protein WRAP73

3

9

High-throughput

0.593

High

731670

STIP1
Stress-induced-phosphoprotein 1

2

20

High-throughput

0.584

High

1026577

HSF1
Heat shock factor protein 1

2

2

High-throughput

0.584

High

516217

HS71B
Heat shock 70 kDa protein 1B

1

20

High-throughput

0.575

High

1250072

ABH15
Protein ABHD15

2

1

High-throughput

0.574

High

1436384

MANS1
MANSC domain-containing protein 1

2

1

High-throughput

0.574

High

447540

NPM
Nucleophosmin

1

2

Small-scale

0.573

High

770931

OPRM
Mu-type opioid receptor

1

1

Small-scale

0.573

High

1153608

MLF2
Myeloid leukemia factor 2

2

7

High-throughput

0.558

High

946213

MLF1
Myeloid leukemia factor 1

2

7

High-throughput

0.549

High

281446

GGYF1
GRB10-interacting GYF protein 1

1

2

High-throughput

0.536

High

406932

MAS
Proto-oncogene Mas

1

3

High-throughput

0.536

High

479884

GSTP1
Glutathione S-transferase P

1

1

High-throughput

0.536

High

894603

GDIB
Rab GDP dissociation inhibitor beta

1

3

High-throughput

0.536

High

990835

1433Z
14-3-3 protein zeta/delta

1

8

High-throughput

0.536

High

1047942

TLE2
Transducin-like enhancer protein 2

1

8

High-throughput

0.536

High

1122916

SIM2
Single-minded homolog 2

1

9

High-throughput

0.536

High

1251120

TPTE2
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2

1

8

High-throughput

0.536

High

1287897

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

6

High-throughput

0.536

High

1396956

MRGX4
Mas-related G-protein coupled receptor member X4

1

3

High-throughput

0.536

High

1408153

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.536

High

1429995

SHRPN
Sharpin

1

1

High-throughput

0.536

High

1458948

CARD8
Caspase recruitment domain-containing protein 8

1

1

High-throughput

0.536

High

1233963

Q6ICH2
single-stranded DNA cytosine deaminase

2

9

High-throughput

0.533

High

844050

HD
Huntingtin

1

6

High-throughput

0.515

High

927593

ATX1
Ataxin-1

1

2

High-throughput

0.515

High

97165

E9PQQ4
Heat shock protein family A

1

20

High-throughput

0.514

High

1328495

M4A15
Membrane-spanning 4-domains subfamily A member 15

1

0

High-throughput

0.513

High

1339986

OR6T1
Olfactory receptor 6T1

1

0

High-throughput

0.513

High

1369507

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

1401845

TGS1
Trimethylguanosine synthase

1

0

High-throughput

0.513

High

1287840

PABP2
Polyadenylate-binding protein 2

1

5

Small-scale

0.508

High

244825

TYW4
tRNA wybutosine-synthesizing protein 4

1

1

High-throughput

0.489

High

1177116

INF2
Inverted formin-2

1

3

High-throughput

0.489

High

1187256

WDR72
WD repeat-containing protein 72

1

10

High-throughput

0.489

High

1197168

KHDC1
KH homology domain-containing protein 1

1

1

High-throughput

0.489

High

1200021

KLH26
Kelch-like protein 26

1

10

High-throughput

0.489

High

1272684

DET1
DET1 homolog

1

1

High-throughput

0.489

High

1292011

NALP8
NACHT, LRR and PYD domains-containing protein 8

1

6

High-throughput

0.489

High

1323932

KLH34
Kelch-like protein 34

1

13

High-throughput

0.489

High

1394848

LOXL4
Lysyl oxidase homolog 4

1

1

High-throughput

0.489

High

261453

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

13

High-throughput

0.481

High

1014643

SMAD3
Mothers against decapentaplegic homolog 3

1

4

High-throughput

0.481

High

1028432

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

High-throughput

0.481

High

168910

PLD2
Phospholipase D2

1

6

High-throughput

0.479

High

218916

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

238633

RAD21
Double-strand-break repair protein rad21 homolog

1

3

High-throughput

0.479

High

243200

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.479

High

260572

BRD4
Bromodomain-containing protein 4

1

15

High-throughput

0.479

High

347976

BAG3
BAG family molecular chaperone regulator 3

1

12

High-throughput

0.479

High

373400

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.479

High

397140

ESR1
Estrogen receptor

1

15

Small-scale

0.479

High

425667

ISG15
Ubiquitin-like protein ISG15

1

14

High-throughput

0.479

High

567511

TCTP
Translationally-controlled tumor protein

1

4

High-throughput

0.479

High

853427

CBX5
Chromobox protein homolog 5

1

2

High-throughput

0.479

High

870008

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

2

High-throughput

0.479

High

895972

F10A1
Hsc70-interacting protein

1

15

High-throughput

0.479

High

983078

RS25
Small ribosomal subunit protein eS25

1

2

High-throughput

0.479

High

988002

GRB2
Growth factor receptor-bound protein 2

1

11

High-throughput

0.479

High

1030707

ANK2
Ankyrin-2

1

3

High-throughput

0.479

High

1098384

ERCC8
DNA excision repair protein ERCC-8

1

11

Small-scale

0.479

High

1114553

CUL3
Cullin-3

1

10

High-throughput

0.479

High

1138720

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

9

High-throughput

0.479

High

1140275

IF4H
Eukaryotic translation initiation factor 4H

1

6

High-throughput

0.479

High

1179386

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

4

High-throughput

0.479

High

1229119

RNF43
E3 ubiquitin-protein ligase RNF43

1

8

High-throughput

0.479

High

1235346

STYK1
Tyrosine-protein kinase STYK1

1

9

High-throughput

0.479

High

1241831

PRP8
Pre-mRNA-processing-splicing factor 8

1

4

High-throughput

0.479

High

1290996

TAXB1
Tax1-binding protein 1

1

4

High-throughput

0.479

High

1332722

ZBT38
Zinc finger and BTB domain-containing protein 38

1

7

Small-scale

0.479

High

1364653

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

5

High-throughput

0.479

High

1367500

ESR2
Estrogen receptor beta

1

14

High-throughput

0.479

High

1380988

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

4

High-throughput

0.479

High

1391574

LTV1
Protein LTV1 homolog

1

3

High-throughput

0.479

High

1434141

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.479

High

1446857

TIGAR
Fructose-2,6-bisphosphatase TIGAR

1

4

High-throughput

0.479

High

1451162

ARGL1
Arginine and glutamate-rich protein 1

1

2

High-throughput

0.479

High

1458943

FBW1B
F-box/WD repeat-containing protein 11

1

12

High-throughput

0.479

High

1458951

ASB4
Ankyrin repeat and SOCS box protein 4

1

16

High-throughput

0.479

High

1128857

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

1324350

PELI3
E3 ubiquitin-protein ligase pellino homolog 3

1

0

High-throughput

0.458

High

1368338

DPF3
Zinc finger protein DPF3

1

0

Small-scale

0.458

High

137364

NPT4
Sodium-dependent phosphate transport protein 4

1

2

High-throughput

0.445

High

220630

AKA10
A-kinase anchor protein 10, mitochondrial

1

1

High-throughput

0.445

High

430462

JUN
Transcription factor Jun

1

6

High-throughput

0.445

High

933544

S12A3
Solute carrier family 12 member 3

1

7

High-throughput

0.445

High

942940

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

5

High-throughput

0.445

High

1117929

BACD2
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

1

8

High-throughput

0.445

High

1199737

KLH22
Kelch-like protein 22

1

10

High-throughput

0.445

High

1215263

SL9C2
Sodium/hydrogen exchanger 11

1

6

High-throughput

0.445

High

1227634

A16L1
Autophagy-related protein 16-1

1

17

High-throughput

0.445

High

1259549

TBA1A
Tubulin alpha-1A chain

1

14

High-throughput

0.445

High

1335766

MOT11
Monocarboxylate transporter 11

1

6

High-throughput

0.445

High

1401552

S26A8
Testis anion transporter 1

1

1

High-throughput

0.445

High

1405534

ZBT18
Zinc finger and BTB domain-containing protein 18

1

10

High-throughput

0.445

High

1430058

KLH25
Kelch-like protein 25

1

4

High-throughput

0.445

High

1458945

S12A4
Solute carrier family 12 member 4

1

6

High-throughput

0.445

High

1458949

S27A6
Long-chain fatty acid transport protein 6

1

3

High-throughput

0.445

High

1458950

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

1

13

High-throughput

0.445

High

1247588

TBPL2
TATA box-binding protein-like 2

1

1

Small-scale

0.439

High

294477

CD123
Translation initiation factor eIF2 assembly protein

1

3

High-throughput

0.437

High

1125080

RCN2
Reticulocalbin-2

1

7

High-throughput

0.437

High

1330612

PLD5
Inactive phospholipase D5

1

2

High-throughput

0.437

High

1397846

CC138
Coiled-coil domain-containing protein 138

1

1

High-throughput

0.437

High

1435023

TM231
Transmembrane protein 231

1

2

High-throughput

0.437

High

1437520

WDR41
WD repeat-containing protein 41

1

10

High-throughput

0.437

High

1458953

CCD61
Centrosomal protein CCDC61

1

1

High-throughput

0.437

High

73468

B2CML4
single-stranded DNA cytosine deaminase

1

9

High-throughput

0.407

High

1108742

TBB3
Tubulin beta-3 chain

1

13

High-throughput

0.407

High

1124798

NUCG
Endonuclease G, mitochondrial

1

3

High-throughput

0.407

High

1215582

Q5TBM3
Heat shock protein family H

1

13

High-throughput

0.407

High

1235392

KLH10
Kelch-like protein 10

1

5

High-throughput

0.407

High

1334189

POC1A
POC1 centriolar protein homolog A

1

11

High-throughput

0.407

High

1383338

ABC3D
DNA dC->dU-editing enzyme APOBEC-3D

1

9

High-throughput

0.407

High

1397884

KLH15
Kelch-like protein 15

1

11

High-throughput

0.407

High

1417807

ANGL4
Angiopoietin-related protein 4

1

0

High-throughput

0.279

Low

1451912

TM260
Protein O-mannosyl-transferase TMEM260

1

0

High-throughput

0.279

Low

296748

TUSC2
Tumor suppressor candidate 2

1

0

High-throughput

0.232

Low

1324960

VW5B2
von Willebrand factor A domain-containing protein 5B2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025