HitPredict

Interactor 1: NIPS2 (O75323)
Protein NipSnap homolog 2 (NipSnap2) (Glioblastoma-amplified sequence)
Gene: NIPSNAP2

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	26043024, 30581152, 34037656, 20562859
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 286 Hs			1 440
+	Hs
		1036851 NIPS1_HUMAN (1-286): 3.13e-155: 436: 68.18		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Mm
		1145343 Q7TMG8_MOUSE (1-286): 1.06e-150: 424: 90.56		SQSTM_MOUSE (1-440): 0: 731: 90.72
+	Hs
		259444 NIPS2_HUMAN (1-286): 1.62e-156: 439: 100.00		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78
+	Hs
		1056111 NIPS1_HUMAN (1-286): 3.13e-155: 436: 68.18		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78