HitPredict

Interactor 1: LIPA2 (O75334)
Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2)
Gene: PPFIA2

Interactor 2: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	9624153
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SAM_1~SAM_1, SAM_1~SAM_2, SAM_2~SAM_2
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007160 - cell-matrix adhesion GO:0030424 - axon GO:0048786 - presynaptic active zone and 1 others more... GO:0050808 - synapse organization
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1257 Hs			1 1202
+	Hs
		259634 LIPA2_HUMAN (1-1257): 1.83e-152: 493: 100.00		LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82
+	Hs
		255242 LIPA3_HUMAN (1-1257): 1.49e-110: 377: 55.59		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		1025277 LIPA1_HUMAN (1-1257): 6.82e-109: 372: 62.89		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		259651 LIPA2_HUMAN (1-1257): 1.83e-152: 493: 100.00		LIPB2_HUMAN (434-1149): 2.41e-95: 327: 18.61
+	Dm
		65321 M9PCD4_DROME (1-1182): 6.32e-99: 345: 42.56		A8DYM0_DROME (860-1122): 3.71e-105: 360: 42.21
+	Hs
		1025318 LIPA1_HUMAN (1-1257): 6.82e-109: 372: 62.89		LIPB2_HUMAN (434-1149): 2.41e-95: 327: 18.61
+	Dm
		65319 A8DYM0_DROME (877-1229): 3.16e-88: 313: 31.03		A8DYM0_DROME (860-1122): 3.71e-105: 360: 42.21
+	Dm
		114427 M9PCD4_DROME (1-1182): 6.32e-99: 345: 42.56		Q9VU88_DROME (604-1148): 6.76e-85: 292: 22.95
+	Hs
		255231 LIPA2_HUMAN (1-1257): 1.83e-152: 493: 100.00		LIPA3_HUMAN (1-265): 3.37e-12: 73.2: 12.45
+	Hs
		259650 LIPA2_HUMAN (1-1257): 1.83e-152: 493: 100.00		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		1146483 KAZRN_HUMAN (439-1215): 5.66e-74: 264: 19.72		KAZRN_HUMAN (426-1152): 1.57e-78: 277: 20.33
+	Dm
		1374287 Q9VU88_DROME (661-1254): 6.63e-69: 247: 17.46		Q9VU88_DROME (604-1148): 6.76e-85: 292: 22.95
+	Hs
		255230 LIPA3_HUMAN (1-1257): 1.49e-110: 377: 55.59		LIPA3_HUMAN (1-265): 3.37e-12: 73.2: 12.45
+	Hs
		255249 LIPA3_HUMAN (1-1257): 1.49e-110: 377: 55.59		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		1025311 LIPA1_HUMAN (1-1257): 6.82e-109: 372: 62.89		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Dm
		114416 M9PCD4_DROME (1-1182): 6.32e-99: 345: 42.56		M9PCD4_DROME (3-277): 4.35e-10: 66.3: 12.59