Protein: RL14A
Large ribosomal subunit protein eL14A (60S ribosomal protein L14-A)

Gene: RL14A, RPL14A
Organism: Saccharomyces cerevisiae S288C
Interactions: 209
UniProt ID: P36105

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0000470 - maturation of LSU-rRNA
GO:0002181 - cytoplasmic translation
GO:0003723 - RNA binding
GO:0003735 - structural constituent of ribosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

433571

RL26A
Large ribosomal subunit protein uL24A

2

3

High-throughput

0.754

High

511171

RL20B
Large ribosomal subunit protein eL20B

2

2

High-throughput

0.754

High

689000

RL16A
Large ribosomal subunit protein uL13A

4

4

High-throughput

0.676

High

689195

RL16B
Large ribosomal subunit protein uL13B

3

4

High-throughput

0.640

High

433005

RL6B
Large ribosomal subunit protein eL6B

1

3

High-throughput

0.618

High

503778

RL27A
Large ribosomal subunit protein eL27A

1

2

High-throughput

0.618

High

503906

RL27B
Large ribosomal subunit protein eL27B

1

2

High-throughput

0.618

High

569756

RL30
Large ribosomal subunit protein eL30

1

1

High-throughput

0.618

High

601019

RL8A
Large ribosomal subunit protein eL8A

1

4

High-throughput

0.618

High

712540

RL8B
Large ribosomal subunit protein eL8B

1

4

High-throughput

0.618

High

781181

RL14B
Large ribosomal subunit protein eL14B

1

1

High-throughput

0.618

High

781207

RL34B
Large ribosomal subunit protein eL34B

1

2

High-throughput

0.618

High

781228

RL26B
Large ribosomal subunit protein uL24B

1

3

High-throughput

0.618

High

781244

RL34A
Large ribosomal subunit protein eL34A

1

2

High-throughput

0.618

High

781249

RL6A
Large ribosomal subunit protein eL6A

1

3

High-throughput

0.618

High

781167

RPF2
Ribosome biogenesis protein RPF2

2

2

High-throughput

0.601

High

781253

GCN5
Histone acetyltransferase GCN5

2

2

High-throughput

0.601

High

781177

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.586

High

781216

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.586

High

410058

RL25
Large ribosomal subunit protein uL23

2

2

High-throughput

0.584

High

432542

RL7A
Large ribosomal subunit protein uL30A

2

5

High-throughput

0.584

High

432825

RL9A
Large ribosomal subunit protein uL6A

2

3

High-throughput

0.584

High

504154

RL31A
Large ribosomal subunit protein eL31A

2

3

High-throughput

0.584

High

750060

MRT4
Ribosome assembly factor MRT4

2

4

Small-scale

0.584

High

781235

NOG2
Nucleolar GTP-binding protein 2

2

4

Small-scale

0.584

High

781273

TMA46
Translation machinery-associated protein 46

2

1

High-throughput

0.584

High

781276

NOP53
Ribosome biogenesis protein NOP53

2

2

Small-scale

0.571

High

689383

RS7A
Small ribosomal subunit protein eS7A

2

0

High-throughput

0.559

High

401971

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

High-throughput

0.553

High

781203

SSB2
Ribosome-associated molecular chaperone SSB2

2

3

High-throughput

0.552

High

781234

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.536

High

781247

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

594318

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.517

High

781182

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.513

High

781223

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

0

High-throughput

0.513

High

781227

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.513

High

781265

SP382
Pre-mRNA-splicing factor SPP382

1

0

Small-scale

0.513

High

517981

SSBP1
Single-stranded nucleic acid-binding protein

1

2

High-throughput

0.501

High

781172

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

2

High-throughput

0.489

High

781256

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

1

High-throughput

0.489

High

781289

SUS1
SAGA complex subunit SUS1

1

1

High-throughput

0.489

High

149695

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

154152

RL36B
Large ribosomal subunit protein eL36B

1

2

High-throughput

0.479

High

383112

RLA4
Large ribosomal subunit protein P2B

1

4

High-throughput

0.479

High

383634

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.479

High

409716

RL24A
Large ribosomal subunit protein eL24A

1

4

High-throughput

0.479

High

415008

RL39
Large ribosomal subunit protein eL39

1

1

High-throughput

0.479

High

427224

RLA0
Large ribosomal subunit protein uL10

1

4

High-throughput

0.479

High

427558

RLA1
Large ribosomal subunit protein P1A

1

4

High-throughput

0.479

High

427687

RLA2
Large ribosomal subunit protein P2A

1

4

High-throughput

0.479

High

433182

RL17A
Large ribosomal subunit protein uL22A

1

4

High-throughput

0.479

High

433998

RL33A
Large ribosomal subunit protein eL33A

1

2

High-throughput

0.479

High

434352

RL15A
Large ribosomal subunit protein eL15A

1

2

High-throughput

0.479

High

434545

RL22A
Large ribosomal subunit protein eL22A

1

3

High-throughput

0.479

High

438669

SC160
Protein SCP160

1

3

High-throughput

0.479

High

441840

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

481998

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

1

High-throughput

0.479

High

503375

RL11A
Large ribosomal subunit protein uL5A

1

3

High-throughput

0.479

High

504520

RL31B
Large ribosomal subunit protein eL31B

1

3

High-throughput

0.479

High

511400

RL43B
Large ribosomal subunit protein eL43B

1

2

High-throughput

0.479

High

511558

RL44B
Large ribosomal subunit protein eL42B

1

2

High-throughput

0.479

High

511922

RS30A
Small ribosomal subunit protein eS30A

1

1

High-throughput

0.479

High

512376

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

512942

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.479

High

513482

RL1A
Large ribosomal subunit protein uL1A

1

3

High-throughput

0.479

High

513668

RL2A
Large ribosomal subunit protein uL2A

1

2

High-throughput

0.479

High

513979

RL18B
Large ribosomal subunit protein eL18B

1

2

High-throughput

0.479

High

514263

RL12B
Large ribosomal subunit protein uL11B

1

2

High-throughput

0.479

High

514576

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

515076

RL19B
Large ribosomal subunit protein eL19

1

2

High-throughput

0.479

High

528809

RLA3
Large ribosomal subunit protein P1B

1

4

High-throughput

0.479

High

531689

RL4A
Large ribosomal subunit protein uL4A

1

3

High-throughput

0.479

High

569970

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

637204

PWP1
Periodic tryptophan protein 1

1

6

High-throughput

0.479

High

663665

RL24B
Large ribosomal subunit protein eL24B

1

4

High-throughput

0.479

High

674548

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

679574

CDC48
Cell division control protein 48

1

3

High-throughput

0.479

High

682242

SPB4
ATP-dependent rRNA helicase SPB4

1

6

High-throughput

0.479

High

684685

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.479

High

739340

ZUO1
Zuotin

1

2

High-throughput

0.479

High

743183

PP12
Serine/threonine-protein phosphatase PP1-2

1

2

Small-scale

0.479

High

746612

DRS1
ATP-dependent RNA helicase DRS1

1

6

High-throughput

0.479

High

753299

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

781169

GBLP
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.479

High

781170

RL32
Large ribosomal subunit protein eL32

1

2

High-throughput

0.479

High

781173

ATG8
Autophagy-related protein 8

1

4

High-throughput

0.479

High

781176

SRP72
Signal recognition particle subunit SRP72

1

1

High-throughput

0.479

High

781188

NMD3
60S ribosomal export protein NMD3

1

1

High-throughput

0.479

High

781190

RPN10
26S proteasome regulatory subunit RPN10

1

1

Small-scale

0.479

High

781192

STM1
Suppressor protein STM1

1

1

High-throughput

0.479

High

781194

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

781196

RBG1
Ribosome-interacting GTPase 1

1

3

High-throughput

0.479

High

781197

IF2P
Eukaryotic translation initiation factor 5B

1

2

High-throughput

0.479

High

781200

NUG1
Nuclear GTP-binding protein NUG1

1

4

High-throughput

0.479

High

781204

RL13B
Large ribosomal subunit protein eL13B

1

2

High-throughput

0.479

High

781209

RLP7
Ribosome biogenesis protein RLP7

1

5

High-throughput

0.479

High

781210

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.479

High

781212

RL17B
Large ribosomal subunit protein uL22B

1

4

High-throughput

0.479

High

781217

RL37A
Large ribosomal subunit protein eL37A

1

2

High-throughput

0.479

High

781219

RL4B
Large ribosomal subunit protein uL4B

1

3

High-throughput

0.479

High

781221

RL37B
Large ribosomal subunit protein eL37B

1

2

High-throughput

0.479

High

781226

LSG1
Large subunit GTPase 1

1

4

High-throughput

0.479

High

781231

PESC
Pescadillo homolog

1

1

High-throughput

0.479

High

781232

SDA1
Protein SDA1

1

1

High-throughput

0.479

High

781237

JJJ1
J protein JJJ1

1

2

High-throughput

0.479

High

781238

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

Small-scale

0.479

High

781239

NOP15
Ribosome biogenesis protein 15

1

3

High-throughput

0.479

High

781243

RL22B
Large ribosomal subunit protein eL22B

1

3

High-throughput

0.479

High

781251

RL21A
Large ribosomal subunit protein eL21A

1

3

High-throughput

0.479

High

781252

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.479

High

781254

HAS1
ATP-dependent RNA helicase HAS1

1

8

High-throughput

0.479

High

781255

CLU
Clustered mitochondria protein 1

1

1

High-throughput

0.479

High

781257

ARX1
Probable metalloprotease ARX1

1

2

High-throughput

0.479

High

781259

HMO1
High mobility group protein 1

1

3

High-throughput

0.479

High

781266

NOC4
Nucleolar complex protein 4

1

2

High-throughput

0.479

High

781269

RIX7
Ribosome biogenesis ATPase RIX7

1

3

High-throughput

0.479

High

781270

REXO4
RNA exonuclease 4

1

2

High-throughput

0.479

High

781280

YRA1
RNA annealing protein YRA1

1

4

High-throughput

0.479

High

781281

RL7B
Large ribosomal subunit protein uL30B

1

5

High-throughput

0.479

High

781282

DBP10
ATP-dependent RNA helicase DBP10

1

7

High-throughput

0.479

High

781285

RL21B
Large ribosomal subunit protein eL21B

1

3

High-throughput

0.479

High

781286

RL13A
Large ribosomal subunit protein eL13A

1

2

High-throughput

0.479

High

781288

RL11B
Large ribosomal subunit protein uL5B

1

3

High-throughput

0.479

High

392559

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.458

High

435004

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

435894

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

436382

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

454993

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

502977

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

597972

NCPR
NADPH--cytochrome P450 reductase

1

0

High-throughput

0.458

High

734816

SRP21
Signal recognition particle subunit SRP21

1

0

High-throughput

0.458

High

737610

HS150
Cell wall mannoprotein HSP150

1

0

High-throughput

0.458

High

747293

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

778260

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

781174

GID4
GID complex substrate-recognition subunit 4

1

0

High-throughput

0.458

High

781178

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

781183

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.458

High

781189

RIX1
Pre-rRNA-processing protein RIX1

1

0

Small-scale

0.458

High

781195

ECM1
Shuttling pre-60S factor ECM1

1

0

High-throughput

0.458

High

781198

NOC2
Nucleolar complex protein 2

1

0

Small-scale

0.458

High

781199

RS26B
Small ribosomal subunit protein eS26B

1

0

High-throughput

0.458

High

781213

ALB1
Ribosome biogenesis protein ALB1

1

0

High-throughput

0.458

High

781215

SEC16
COPII coat assembly protein SEC16

1

0

High-throughput

0.458

High

781218

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.458

High

781224

DXO
Decapping nuclease RAI1

1

0

High-throughput

0.458

High

781230

SLX9
Ribosome biogenesis protein SLX9

1

0

High-throughput

0.458

High

781248

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

781260

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

781261

LTN1
E3 ubiquitin-protein ligase listerin

1

0

Small-scale

0.458

High

781267

ELP1
Elongator complex protein 1

1

0

High-throughput

0.458

High

781271

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

781277

CHS5
Chitin biosynthesis protein CHS5

1

0

High-throughput

0.458

High

781279

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

781287

EFG1P
rRNA-processing protein EFG1

1

0

Small-scale

0.458

High

544476

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

746028

YME2
Mitochondrial escape protein 2

1

1

High-throughput

0.445

High

781184

RPF1
Ribosome production factor 1

1

2

High-throughput

0.445

High

558677

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.437

High

567677

ACOX
Acyl-coenzyme A oxidase

1

1

High-throughput

0.437

High

597115

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.437

High

597434

EF3A
Elongation factor 3A

1

1

High-throughput

0.437

High

706792

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

744284

CHD1
Chromo domain-containing protein 1

1

4

High-throughput

0.437

High

781168

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.437

High

781171

RDH54
DNA repair and recombination protein RDH54

1

4

High-throughput

0.437

High

781175

PHO88
SRP-independent targeting protein 3

1

1

High-throughput

0.437

High

781180

ECM29
Proteasome component ECM29

1

1

High-throughput

0.437

High

781193

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.437

High

781201

ARB1
ABC transporter ATP-binding protein ARB1

1

1

Small-scale

0.437

High

781208

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

781211

ELP2
Elongator complex protein 2

1

3

High-throughput

0.437

High

781214

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

781222

SKP1
Suppressor of kinetochore protein 1

1

1

Small-scale

0.437

High

781225

VID30
GID complex subunit 1

1

1

High-throughput

0.437

High

781229

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.437

High

781233

H1
Histone H1

1

1

High-throughput

0.437

High

781236

GIS2
Zinc finger protein GIS2

1

3

High-throughput

0.437

High

781240

NST1
Stress response protein NST1

1

2

High-throughput

0.437

High

781242

ORC1
Origin recognition complex subunit 1

1

3

High-throughput

0.437

High

781245

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.437

High

781246

PTA1
Pre-tRNA-processing protein PTA1

1

1

Small-scale

0.437

High

781250

ABF2
ARS-binding factor 2, mitochondrial

1

4

High-throughput

0.437

High

781258

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.437

High

781268

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

781283

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.437

High

781290

ENV10
SRP-independent targeting protein 2

1

1

High-throughput

0.437

High

781191

BFR1
Nuclear segregation protein BFR1

1

0

High-throughput

0.426

High

781278

MED2
Mediator of RNA polymerase II transcription subunit 2

1

0

High-throughput

0.426

High

781185

TOM71
Protein TOM71

1

1

High-throughput

0.407

High

781263

RQC1
Ribosome quality control complex subunit 1

2

0

Small-scale

0.305

High

678832

AHC2
ADA histone acetyltransferase complex component 2

1

0

High-throughput

0.279

Low

781220

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.279

Low

781262

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.279

Low

781275

HFI1
SAGA complex subunit HFI1

1

0

High-throughput

0.279

Low

649602

KCC2
Calcium/calmodulin-dependent protein kinase II

1

0

High-throughput

0.249

Low

661498

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

666437

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.249

Low

709698

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

781179

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.249

Low

781186

YHS7
Uncharacterized protein YHR127W

1

0

High-throughput

0.249

Low

781187

CRP1
Cruciform DNA-recognizing protein 1 [Cleaved into: CRP1 short N-terminal subpeptide; CRP1 short C-terminal subpeptide]

1

0

High-throughput

0.249

Low

781202

YEY6
MYG1 protein YER156C

1

0

Small-scale

0.249

Low

781205

YIQ1
Uncharacterized protein YIL161W

1

0

High-throughput

0.249

Low

781206

TM108
Protein TMA108

1

0

High-throughput

0.249

Low

781241

FAP1
FKBP12-associated protein 1

1

0

High-throughput

0.249

Low

781264

YL278
Uncharacterized transcriptional regulatory protein YLR278C

1

0

High-throughput

0.249

Low

781272

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

781274

KAD6
Adenylate kinase isoenzyme 6 homolog FAP7

1

0

Small-scale

0.249

Low

781284

RQC2
Ribosome quality control complex subunit 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025