HitPredict

Interactor 1: PDCD6 (O75340)
Programmed cell death protein 6 (Apoptosis-linked gene 2 protein homolog) (ALG-2)
Gene: PDCD6

Interactor 2: PDCD6 (O75340)
Programmed cell death protein 6 (Apoptosis-linked gene 2 protein homolog) (ALG-2)
Gene: PDCD6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.899

The method score is based on:

Property Details
Experiments 25416956, 16189514, 21988832, 18940611
Identification Methods two hybrid, two hybrid array, x-ray crystallography, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~EF-hand_7
Common GO terms GO:0000287 - magnesium ion binding
GO:0001525 - angiogenesis
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0005509 - calcium ion binding
GO:0005634 - nucleus
and 33 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 191
Hs

1 191
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024