Interactor 1: PDCD6 (O75340)
Programmed cell death protein 6 (Apoptosis-linked gene 2 protein homolog) (ALG-2)
Gene: PDCD6

Interactor 2: PDC6I (Q8WUM4)
Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (Hp95)
Gene: PDCD6IP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.757

The method score is based on:

Property Details
Experiments 27716508, 9880530, 11883939, 35271311, 18940611, 18256029, 17196169, 31515488
Identification Methods affinity chromatography technology, pull down, two hybrid, unspecified method, x-ray crystallography, far western blotting, anti tag coimmunoprecipitation, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005768 - endosome
GO:0005829 - cytosol
GO:0042803 - protein homodimerization activity
GO:0048306 - calcium-dependent protein binding
GO:0070062 - extracellular exosome
and 1 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 191
Hs

1 868
+ Mm
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm

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Last updated: 15 Jul 2024