HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31239290, 35987950
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 344
+	Hs
		259850 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		SRSF1_HUMAN (3-188): 3.03e-54: 180: 36.65
+	Hs
		260402 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		RBM4_HUMAN (1-343): 1.67e-48: 168: 17.05
+	Hs
		259891 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		SRSF9_HUMAN (3-222): 5.62e-49: 165: 34.22
+	Hs
		259360 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		PABP1_HUMAN (100-191): 9.12e-12: 68: 19.59
+	Hs
		259793 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		SRSF3_HUMAN (3-78): 2.42e-09: 57.4: 46.84
+	Hs
		1060992 BRD3_HUMAN (37-737): 8.76e-57: 213: 47.73		SRSF1_HUMAN (3-188): 3.03e-54: 180: 36.65
+	Hs
		1098968 BRD3_HUMAN (37-737): 8.76e-57: 213: 47.73		SRSF9_HUMAN (3-222): 5.62e-49: 165: 34.22
+	Hs
		674156 BRD2_HUMAN (3-737): 5.3e-54: 206: 46.43		SRSF9_HUMAN (3-222): 5.62e-49: 165: 34.22
+	Zm
		19452 A0A1D6HCG5_MAIZE (43-242): 1.58e-37: 153: 25.00		Q64HC3_MAIZE (4-281): 4.99e-49: 167: 37.41
+	Hs
		1061166 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		SRSF1_HUMAN (3-188): 3.03e-54: 180: 36.65
+	Hs
		1062125 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		SRSF4_HUMAN (1-323): 1.86e-45: 163: 63.47
+	Hs
		1099265 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		SRSF5_HUMAN (2-180): 3.8e-46: 160: 64.25
+	Hs
		1099557 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		SRSF6_HUMAN (1-322): 1.01e-43: 155: 100.00
+	Sc
		1031037 GCN5_YEAST (140-462): 2.78e-42: 163: 14.41		NOP3_YEAST (3-326): 1.2e-19: 91.2: 19.94
+	Hs
		1098979 BRDT_HUMAN (1080-1361): 2.17e-09: 64.3: 27.59		SRSF9_HUMAN (3-222): 5.62e-49: 165: 34.22
+	Sc
		763003 SPT7_YEAST (223-611): 5.84e-25: 115: 12.21		NOP3_YEAST (3-326): 1.2e-19: 91.2: 19.94
+	Hs
		550481 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		PABP1_HUMAN (100-191): 9.12e-12: 68: 19.59