HitPredict

Interactor 1: FKBP6 (O75344)
Inactive peptidyl-prolyl cis-trans isomerase FKBP6 (Inactive PPIase FKBP6) (36 kDa FK506-binding protein) (36 kDa FKBP) (FKBP-36) (FK506-binding protein 6) (FKBP-6) (Immunophilin FKBP36)
Gene: FKBP6

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	25416956, 25910212, 31515488
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, two hybrid bait and prey pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 669
+	Hs
		259918 FKBP6_HUMAN (1-327): 4.19e-82: 253: 100.00		MYH1_HUMAN (152-661): 8.43e-14: 77.4: 8.93
+	Hs
		259986 FKBP6_HUMAN (1-327): 4.19e-82: 253: 100.00		MYH4_HUMAN (261-669): 1.55e-12: 73.1: 12.32
+	Hs
		259920 FKBP6_HUMAN (1-327): 4.19e-82: 253: 100.00		MYH8_HUMAN (196-572): 6.41e-09: 61.6: 9.26
+	Hs
		259919 FKBP6_HUMAN (1-327): 4.19e-82: 253: 100.00		MYH7_HUMAN (140-540): 9.01e-09: 61.2: 9.45
+	Hs
		1234880 TTC9C_HUMAN (164-316): 3.12e-47: 158: 28.07		LZTS1_HUMAN (26-653): 2.54e-34: 140: 35.06
+	Hs
		1132675 AIPL1_HUMAN (36-317): 4.56e-56: 188: 17.90		FKB15_HUMAN (49-548): 5.14e-10: 65: 9.00
+	Hs
		1234886 TTC9C_HUMAN (164-316): 3.12e-47: 158: 28.07		MRCKB_HUMAN (197-560): 2.09e-10: 66.2: 13.44