HitPredict

Interactor 1: VATG1 (O75348)
V-type proton ATPase subunit G 1 (V-ATPase subunit G 1) (V-ATPase 13 kDa subunit 1) (Vacuolar proton pump subunit G 1) (Vacuolar proton pump subunit M16)
Gene: ATP6V1G1

Interactor 2: VATA (P38606)
V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar ATPase isoform VA68) (Vacuolar proton pump subunit alpha)
Gene: ATP6V1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

The method score is based on:

Property	Details
Experiments	35271311, 33961781, 21674799
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain GO:0005765 - lysosomal membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006879 - intracellular iron ion homeostasis and 8 others more... GO:0016241 - regulation of macroautophagy GO:0016324 - apical plasma membrane GO:0016887 - ATP hydrolysis activity GO:0036295 - cellular response to increased oxygen levels GO:0046961 - proton-transporting ATPase activity, rotational mechanism GO:0070062 - extracellular exosome GO:0097401 - synaptic vesicle lumen acidification GO:1902495 - transmembrane transporter complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	118
Hs

1	617

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024