HitPredict

Interactor 1: TP4A3 (O75365)
Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
Gene: PTP4A3

Interactor 2: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28675297
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 173 Hs			1 457
+	Hs
		890648 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00
+	Mm
		139417 PTEN_MOUSE (5-163): 2.46e-41: 144: 18.86		FKBP5_MOUSE (1-457): 1.26e-140: 412: 86.87
+	Hs
		985173 DUS2_HUMAN (2-154): 7.14e-31: 115: 18.71		FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00
+	Hs
		118722 DUS2_HUMAN (2-154): 7.14e-31: 115: 18.71		AIP_HUMAN (144-414): 1.52e-49: 173: 16.72
+	Hs
		684826 TPTE2_HUMAN (6-168): 1.11e-42: 150: 15.85		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Hs
		684811 TENS3_HUMAN (4-168): 1.59e-40: 147: 14.84		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Hs
		684565 TPTE_HUMAN (6-168): 3.19e-40: 144: 15.30		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Hs
		684577 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Sc
		690637 CDC14_YEAST (11-169): 1.4e-37: 137: 22.73		FKBP2_YEAST (129-251): 1.64e-23: 97.6: 22.31
+	Mm
		139411 PTEN_MOUSE (5-163): 2.46e-41: 144: 18.86		FKB10_MOUSE (134-285): 1e-11: 69.1: 19.23