HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28242625
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0031492 - nucleosomal DNA binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 1214
+	Hs
		260956 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		555557 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		1151361 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		555574 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		260909 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		MYSM1_HUMAN (276-523): 7.61e-53: 202: 22.96
+	Sc
		392479 H2A2_YEAST (14-123): 1.54e-41: 144: 67.27		RSC8_YEAST (336-751): 4.61e-104: 342: 28.30
+	Sc
		392356 H2A2_YEAST (14-123): 1.54e-41: 144: 67.27		SWI3_YEAST (254-793): 1.23e-96: 329: 26.48
+	Sc
		392086 H2A1_YEAST (14-123): 2.85e-41: 143: 67.27		SWI3_YEAST (254-793): 1.23e-96: 329: 26.48
+	Hs
		555498 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		MYSM1_HUMAN (276-523): 7.61e-53: 202: 22.96
+	Hs
		391742 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		MYSM1_HUMAN (276-523): 7.61e-53: 202: 22.96
+	Hs
		1087021 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		MYSM1_HUMAN (276-523): 7.61e-53: 202: 22.96
+	Mm
		1149044 H2A2A_MOUSE (1-126): 8.18e-65: 203: 63.57		MYSM1_MOUSE (276-523): 3.33e-50: 194: 19.16
+	Hs
		231959 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Hs
		391610 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		SC24C_HUMAN (1005-1213): 5.27e-13: 75.8: 19.28
+	Hs
		391802 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		KMT2C_HUMAN (650-1128): 8.15e-09: 62.4: 8.57
+	Mm
		70932 H2A3_MOUSE (1-126): 8.92e-65: 203: 62.79		EP300_MOUSE (885-1214): 8.74e-09: 62.4: 13.78