Protein: FADS2
Acyl-CoA 6-desaturase (EC 1.14.19.3) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase) (Fatty acid desaturase 2)

Gene: FADS2
Organism: Homo sapiens
Interactions: 67
UniProt ID: O95864

Gene Ontology (top 5):
GO:0002538 - arachidonic acid metabolite production involved in inflammatory response
GO:0004768 - stearoyl-CoA 9-desaturase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0006629 - lipid metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

326900

FADS3
Fatty acid desaturase 3

1

12

High-throughput

0.691

High

326899

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

1

High-throughput

0.618

High

326893

DJC25
DnaJ homolog subfamily C member 25

1

0

High-throughput

0.586

High

326873

K1H1
Keratin, type I cuticular Ha1

2

1

High-throughput

0.553

High

326876

K1C40
Keratin, type I cytoskeletal 40

2

1

High-throughput

0.553

High

326850

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.536

High

326862

PSN1
Presenilin-1

1

1

High-throughput

0.536

High

160990

CLGN
Calmegin

1

1

High-throughput

0.515

High

326892

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.513

High

326846

APOB
Apolipoprotein B-100

1

0

High-throughput

0.493

High

48218

ESYT2
Extended synaptotagmin-2

1

2

High-throughput

0.479

High

126989

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

1

High-throughput

0.479

High

163711

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

2

High-throughput

0.479

High

204888

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

326847

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

326848

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.479

High

326849

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

2

High-throughput

0.479

High

326853

ANDR
Androgen receptor

1

2

High-throughput

0.479

High

326854

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

326858

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

3

Small-scale

0.479

High

326863

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.479

High

326864

RAB7A
Ras-related protein Rab-7a

1

4

High-throughput

0.479

High

326867

SC61B
Protein transport protein Sec61 subunit beta

1

3

High-throughput

0.479

High

326869

VIGLN
Vigilin

1

1

High-throughput

0.479

High

326872

CUL3
Cullin-3

1

1

High-throughput

0.479

High

326874

CAH9
Carbonic anhydrase 9

1

1

High-throughput

0.479

High

326885

RN139
E3 ubiquitin-protein ligase RNF139

1

2

High-throughput

0.479

High

326886

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

2

High-throughput

0.479

High

326890

SEC62
Translocation protein SEC62

1

2

High-throughput

0.479

High

326891

DERL1
Derlin-1

1

1

High-throughput

0.479

High

326894

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

326898

AMFR
E3 ubiquitin-protein ligase AMFR

1

3

High-throughput

0.479

High

326856

CCNF
Cyclin-F

1

1

High-throughput

0.470

High

326852

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.470

High

326843

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

326855

TGFR2
TGF-beta receptor type-2

1

0

High-throughput

0.458

High

326857

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

326865

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

0

High-throughput

0.458

High

326871

CLN3
Battenin

1

0

Small-scale

0.458

High

326883

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.458

High

326866

CD81
CD81 antigen

1

4

High-throughput

0.445

High

326851

ATX1L
Ataxin-1-like

1

1

High-throughput

0.439

High

326880

NT2NA
Notch homolog 2 N-terminal-like protein A

1

1

High-throughput

0.439

High

226178

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.437

High

326844

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

326859

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.437

High

326860

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

326868

RNF4
E3 ubiquitin-protein ligase RNF4

1

5

High-throughput

0.437

High

326877

TECT3
Tectonic-3

1

2

High-throughput

0.437

High

326878

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

326882

DHB11
Estradiol 17-beta-dehydrogenase 11

1

2

High-throughput

0.437

High

326888

TECT2
Tectonic-2

1

2

High-throughput

0.437

High

326897

OTULL
Inactive ubiquitin thioesterase OTULINL

1

3

High-throughput

0.437

High

326881

ZN655
Zinc finger protein 655

2

0

High-throughput

0.316

High

326875

LELP1
Late cornified envelope-like proline-rich protein 1

1

0

High-throughput

0.269

Low

326884

CC110
Coiled-coil domain-containing protein 110

1

0

High-throughput

0.269

Low

326887

SPDLY
Protein Spindly

1

0

High-throughput

0.269

Low

326895

PANK3
Pantothenate kinase 3

1

0

High-throughput

0.269

Low

326896

GPBL1
Vasculin-like protein 1

1

0

High-throughput

0.269

Low

451

NBPFJ
Neuroblastoma breakpoint family member 19

1

0

High-throughput

0.251

Low

326870

GRSF1
G-rich sequence factor 1

1

0

Small-scale

0.251

Low

47733

RBM47
RNA-binding protein 47

1

0

High-throughput

0.249

Low

326845

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

326861

CTCF
Transcriptional repressor CTCF

1

0

Small-scale

0.249

Low

326879

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

872

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

326889

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024