HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: TSHR (P16473)
Thyrotropin receptor (Thyroid-stimulating hormone receptor) (TSH-R)
Gene: TSHR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	0.60	0.408

Property	Details
Experiments	8327473
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 764
+	Hs
		428914 FLNA_HUMAN (1-2602): 0: 2661: 69.59		ADRB2_HUMAN (393-721): 1.48e-63: 219: 17.52
+	Hs
		598007 FLNA_HUMAN (1-2602): 0: 2661: 69.59		MTR1B_HUMAN (399-701): 6.85e-64: 219: 21.56
+	Hs
		825709 Q60FE5_HUMAN (1-2602): 0: 2660: 69.59		MTR1B_HUMAN (399-701): 6.85e-64: 219: 21.56
+	Hs
		598004 FLNA_HUMAN (1-2602): 0: 2661: 69.59		MTR1A_HUMAN (417-700): 3.23e-63: 217: 20.60
+	Hs
		815890 Q60FE5_HUMAN (1-2602): 0: 2660: 69.59		MTR1A_HUMAN (417-700): 3.23e-63: 217: 20.60
+	Hs
		626688 FLNC_HUMAN (6-2602): 0: 1470: 35.38		ADA1D_HUMAN (419-689): 4.53e-63: 223: 16.05
+	Hs
		722936 FLNC_HUMAN (6-2602): 0: 1470: 35.38		ADA1A_HUMAN (386-704): 3.75e-64: 223: 15.62
+	Hs
		723009 FLNC_HUMAN (6-2602): 0: 1470: 35.38		ADA1B_HUMAN (399-697): 6.33e-61: 216: 16.67
+	Hs
		521497 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		MTR1B_HUMAN (399-701): 6.85e-64: 219: 21.56
+	Hs
		521496 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		MTR1A_HUMAN (417-700): 3.23e-63: 217: 20.60
+	Hs
		825763 MACF1_HUMAN (16-239): 9.3e-35: 149: 40.69		MTR1B_HUMAN (399-701): 6.85e-64: 219: 21.56