Protein: NB5R1
NADH-cytochrome b5 reductase 1 (b5R.1) (EC 1.6.2.2) (Humb5R2) (NAD(P)H:quinone oxidoreductase type 3 polypeptide A2)

Gene: NB5R1, CYB5R1
Organism: Homo sapiens
Interactions: 93
UniProt ID: Q9UHQ9

Gene Ontology (top 5):
GO:0004128 - cytochrome-b5 reductase activity, acting on NAD(P)H
GO:0005739 - mitochondrion
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

722656

CTR1
High affinity cationic amino acid transporter 1

3

8

High-throughput

0.662

High

1340579

MFSD8
Major facilitator superfamily domain-containing protein 8

3

2

High-throughput

0.662

High

1034843

NAAA
N-acylethanolamine-hydrolyzing acid amidase

3

0

High-throughput

0.638

High

1351241

MCLN3
Mucolipin-3

3

0

High-throughput

0.638

High

648843

KCNA5
Potassium voltage-gated channel subfamily A member 5

2

2

High-throughput

0.628

High

1359368

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

4

High-throughput

0.628

High

1459922

I20RA
Interleukin-20 receptor subunit alpha

2

1

High-throughput

0.628

High

1460053

PCDG5
Protocadherin gamma-A5

2

3

High-throughput

0.628

High

174139

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

2

7

High-throughput

0.611

High

71407

HECA2
HEPACAM family member 2

3

1

High-throughput

0.609

High

226906

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

2

4

High-throughput

0.606

High

1389518

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

4

High-throughput

0.606

High

1405815

TTC1
Tetratricopeptide repeat protein 1

2

3

High-throughput

0.606

High

1450324

CC50A
Cell cycle control protein 50A

2

0

High-throughput

0.602

High

1348654

S7A14
Solute carrier family 7 member 14

2

8

High-throughput

0.601

High

243221

PRKN
E3 ubiquitin-protein ligase parkin

2

6

Small-scale

0.584

High

71178

HIG1C
HIG1 domain family member 1C

2

0

High-throughput

0.580

High

1289168

OSTB
Organic solute transporter subunit beta

2

0

High-throughput

0.580

High

1460049

UBQL1
Ubiquilin-1

1

4

High-throughput

0.573

High

1402733

TCPQM
T-complex protein 1 subunit theta-like 2

2

5

High-throughput

0.549

High

1327811

SH2D3
SH2 domain-containing protein 3C

2

0

High-throughput

0.547

High

1448806

UBQL4
Ubiquilin-4

1

6

High-throughput

0.541

High

332372

5HT3B
5-hydroxytryptamine receptor 3B

1

4

High-throughput

0.536

High

349601

TSN15
Tetraspanin-15

1

5

High-throughput

0.536

High

595121

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

2

High-throughput

0.536

High

608007

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

3

High-throughput

0.536

High

723271

ACHB4
Neuronal acetylcholine receptor subunit beta-4

1

2

High-throughput

0.536

High

733458

CCR1
C-C chemokine receptor type 1

1

2

High-throughput

0.536

High

851237

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

2

High-throughput

0.536

High

1023907

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

2

High-throughput

0.536

High

1048807

ACHE
Acetylcholine receptor subunit epsilon

1

3

High-throughput

0.536

High

1310505

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

1329605

I22R1
Interleukin-22 receptor subunit alpha-1

1

1

High-throughput

0.536

High

1363247

AQP3
Aquaporin-3

1

1

High-throughput

0.536

High

1372416

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

7

High-throughput

0.536

High

1417088

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

5

High-throughput

0.536

High

1417694

TX101
Testis-expressed protein 101

1

1

High-throughput

0.536

High

1429307

S22A4
Solute carrier family 22 member 4

1

3

High-throughput

0.536

High

1460051

PCDGL
Protocadherin gamma-C4

1

3

High-throughput

0.536

High

1460052

PCDGE
Protocadherin gamma-B2

1

3

High-throughput

0.536

High

1460054

PCDAB
Protocadherin alpha-11

1

3

High-throughput

0.536

High

190513

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.513

High

593528

PGFRA
Platelet-derived growth factor receptor alpha

1

0

High-throughput

0.513

High

771827

SCN4A
Sodium channel protein type 4 subunit alpha

1

0

High-throughput

0.513

High

1055149

CCG1
Voltage-dependent calcium channel gamma-1 subunit

1

0

High-throughput

0.513

High

1195465

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.513

High

1203825

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

1210040

LY66F
Lymphocyte antigen 6 complex locus protein G6f

1

0

High-throughput

0.513

High

1254088

LRC55
Leucine-rich repeat-containing protein 55

1

0

High-throughput

0.513

High

1382089

T106A
Transmembrane protein 106A

1

0

High-throughput

0.513

High

1432445

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

1438491

RXFP1
Relaxin receptor 1

1

0

High-throughput

0.513

High

662669

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

1

High-throughput

0.489

High

848587

MAGA8
Melanoma-associated antigen 8

1

2

High-throughput

0.489

High

1249766

BTNL3
Butyrophilin-like protein 3

1

3

High-throughput

0.489

High

1454526

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

1

High-throughput

0.489

High

1460050

SSUH2
Protein SSUH2 homolog

1

1

High-throughput

0.489

High

275128

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.479

High

279232

ULK1
Serine/threonine-protein kinase ULK1

1

1

Small-scale

0.479

High

374263

RASN
GTPase NRas

1

3

High-throughput

0.479

High

376064

RASK
GTPase KRas

1

3

High-throughput

0.479

High

418501

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

3

High-throughput

0.479

High

508791

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

6

High-throughput

0.479

High

716397

BLVRB
Flavin reductase

1

4

High-throughput

0.479

High

1192298

ZACN
Ligand-gated cation channel ZACN

1

4

High-throughput

0.479

High

1205502

EMC4
ER membrane protein complex subunit 4

1

1

High-throughput

0.479

High

1330432

EMC1
ER membrane protein complex subunit 1

1

2

High-throughput

0.479

High

1366616

AKAP1
A-kinase anchor protein 1, mitochondrial

1

2

High-throughput

0.479

High

1367521

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

1414498

DERL1
Derlin-1

1

3

High-throughput

0.479

High

1447401

ANLN
Anillin

1

2

High-throughput

0.479

High

1451744

OCAD1
OCIA domain-containing protein 1

1

1

High-throughput

0.479

High

1460055

MTCH2
Mitochondrial carrier homolog 2

1

4

High-throughput

0.479

High

1401254

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1451787

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

0

Small-scale

0.458

High

231650

PRKY
Putative serine/threonine-protein kinase PRKY

1

3

High-throughput

0.445

High

261307

NSMA
Sphingomyelin phosphodiesterase 2

1

1

High-throughput

0.445

High

653648

HEMH
Ferrochelatase, mitochondrial

1

2

High-throughput

0.445

High

841274

CNDD3
Condensin-2 complex subunit D3

1

1

High-throughput

0.445

High

845156

EAA3
Excitatory amino acid transporter 3

1

1

High-throughput

0.445

High

1227648

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.445

High

1361329

CTR3
Cationic amino acid transporter 3

1

8

High-throughput

0.445

High

1460056

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

2

High-throughput

0.445

High

589974

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

696796

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

769448

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1255985

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1139601

S39AE
Metal cation symporter ZIP14

1

0

High-throughput

0.426

High

1308796

S41A1
Solute carrier family 41 member 1

1

0

High-throughput

0.426

High

1350637

SFXN5
Sideroflexin-5

1

0

High-throughput

0.426

High

1359272

CA054
Uncharacterized protein C1orf54

2

0

High-throughput

0.313

High

1101439

SG2A2
Mammaglobin-A

1

0

High-throughput

0.279

Low

1389618

SAAL1
Protein SAAL1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025