HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: UBP14 (P54578)
Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14)
Gene: USP14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30425250
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 494
+	Hs
		598024 FLNA_HUMAN (1-2602): 0: 2661: 69.59		UBP14_HUMAN (1-494): 7.04e-147: 431: 100.00
+	Hs
		598357 FLNA_HUMAN (1-2602): 0: 2661: 69.59		UBP36_HUMAN (65-482): 3.73e-90: 299: 17.54
+	Hs
		870803 FLNC_HUMAN (6-2602): 0: 1470: 35.38		UBP14_HUMAN (1-494): 7.04e-147: 431: 100.00
+	Hs
		521511 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		UBP14_HUMAN (1-494): 7.04e-147: 431: 100.00
+	Hs
		870758 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		UBP14_HUMAN (1-494): 7.04e-147: 431: 100.00
+	Hs
		211543 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		UBP14_HUMAN (1-494): 7.04e-147: 431: 100.00
+	Hs
		271077 ACTN3_HUMAN (5-364): 1.21e-118: 402: 26.88		UBP2_HUMAN (56-487): 5.71e-90: 288: 16.30
+	Hs
		271026 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		UBP2_HUMAN (56-487): 5.71e-90: 288: 16.30
+	Hs
		271040 ACTN2_HUMAN (5-364): 2.6e-116: 395: 26.61		UBP2_HUMAN (56-487): 5.71e-90: 288: 16.30
+	Hs
		870933 MACF1_HUMAN (16-239): 9.3e-35: 149: 40.69		UBP14_HUMAN (1-494): 7.04e-147: 431: 100.00