Protein: BROX
BRO1 domain-containing protein BROX (BRO1 domain- and CAAX motif-containing protein)

Gene: BROX
Organism: Homo sapiens
Interactions: 38
UniProt ID: Q5VW32

Gene Ontology (top 5):
GO:0005635 - nuclear envelope
GO:0007084 - mitotic nuclear membrane reassembly
GO:0031965 - nuclear membrane
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1218797

CHM4B
Charged multivesicular body protein 4b

2

14

Small-scale

0.634

High

1218785

BROX
BRO1 domain-containing protein BROX

1

5

High-throughput

0.618

High

1218801

CHMP5
Charged multivesicular body protein 5

1

14

Small-scale

0.578

High

1218799

CHM1A
Charged multivesicular body protein 1a

1

10

High-throughput

0.536

High

389418

FINC
Fibronectin

1

0

High-throughput

0.513

High

1218795

IPO9
Importin-9

1

0

High-throughput

0.513

High

466307

RHOC
Rho-related GTP-binding protein RhoC

1

5

High-throughput

0.479

High

978075

RHOB
Rho-related GTP-binding protein RhoB

1

5

High-throughput

0.479

High

1218791

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

3

High-throughput

0.445

High

1218800

ITM2C
Integral membrane protein 2C

1

2

High-throughput

0.445

High

106098

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

241956

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.437

High

253359

JAK2
Tyrosine-protein kinase JAK2

1

8

High-throughput

0.437

High

260071

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.437

High

588899

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

695680

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

768401

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1218786

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1218788

CGAS
Cyclic GMP-AMP synthase

1

1

High-throughput

0.437

High

1218794

CHM4C
Charged multivesicular body protein 4c

1

14

Small-scale

0.437

High

1218796

CHM4A
Charged multivesicular body protein 4a

1

14

Small-scale

0.437

High

142352

PEX7
Peroxisomal targeting signal 2 receptor

1

2

High-throughput

0.407

High

190385

COPT1
High affinity copper uptake protein 1

1

1

High-throughput

0.407

High

261192

NSMA
Sphingomyelin phosphodiesterase 2

1

1

High-throughput

0.407

High

330196

VENTX
Homeobox protein VENTX

1

2

High-throughput

0.407

High

1103985

RM49
Large ribosomal subunit protein mL49

1

2

High-throughput

0.407

High

1218790

MFSD8
Major facilitator superfamily domain-containing protein 8

1

1

High-throughput

0.407

High

1218802

GAB2
GRB2-associated-binding protein 2

1

2

High-throughput

0.407

High

654643

TCEA1
Transcription elongation factor A protein 1

2

0

High-throughput

0.324

High

1218789

RN149
E3 ubiquitin-protein ligase RNF149

2

0

High-throughput

0.318

High

659686

NFYA
Nuclear transcription factor Y subunit alpha

1

0

High-throughput

0.279

Low

1218798

ZDHC6
Palmitoyltransferase ZDHHC6

1

0

High-throughput

0.279

Low

74515

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.269

Low

1218787

CEP68
Centrosomal protein of 68 kDa

1

0

High-throughput

0.249

Low

1218793

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.249

Low

598741

ANFB
Natriuretic peptides B

1

0

High-throughput

0.232

Low

1218792

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025