HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	33022573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 334
+	Hs
		598040 FLNA_HUMAN (1-2602): 0: 2661: 69.59		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		597996 FLNA_HUMAN (1-2602): 0: 2661: 69.59		LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49
+	Hs
		598240 FLNA_HUMAN (1-2602): 0: 2661: 69.59		POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89
+	Hs
		598298 FLNA_HUMAN (1-2602): 0: 2661: 69.59		WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83
+	Hs
		598209 FLNA_HUMAN (1-2602): 0: 2661: 69.59		WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10
+	Hs
		598147 FLNA_HUMAN (1-2602): 0: 2661: 69.59		SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71
+	Hs
		598345 FLNA_HUMAN (1-2602): 0: 2661: 69.59		NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54
+	Hs
		598260 FLNA_HUMAN (1-2602): 0: 2661: 69.59		FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15
+	Hs
		598268 FLNA_HUMAN (1-2602): 0: 2661: 69.59		SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29
+	Hs
		903137 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		903607 MACF1_HUMAN (16-239): 9.3e-35: 149: 40.69		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		957555 PGBM_HUMAN (1199-2602): 3.08e-68: 259: 13.76		FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15
+	Hs
		957556 PGBM_HUMAN (1199-2602): 3.08e-68: 259: 13.76		SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29
+	Hs
		1281478 MACF1_HUMAN (16-239): 9.3e-35: 149: 40.69		FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15
+	Dm
		1375914 X2JE09_DROME (296-647): 2.5e-14: 81.9: 13.12		FBXW7_DROME (40-169): 6.72e-18: 86.7: 39.10