Protein: LAT2
Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2) (Solute carrier family 7 member 8)

Gene: LAT2, SLC7A8
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q9UHI5

Gene Ontology (top 5):
GO:0003333 - amino acid transmembrane transport
GO:0005886 - plasma membrane
GO:0006865 - amino acid transport
GO:0009925 - basal plasma membrane
GO:0015101 - organic cation transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

467645

4F2
Amino acid transporter heavy chain SLC3A2

4

11

High-throughput

0.890

High

188605

SIGL5
Sialic acid-binding Ig-like lectin 5

2

6

High-throughput

0.783

High

1060403

SLC31
Amino acid transporter heavy chain SLC3A1

1

11

Small-scale

0.618

High

261306

NSMA
Sphingomyelin phosphodiesterase 2

2

1

High-throughput

0.606

High

642311

COMT
Catechol O-methyltransferase

2

2

High-throughput

0.606

High

1411159

ZNT2
Proton-coupled zinc antiporter SLC30A2

2

1

High-throughput

0.606

High

1453240

NINJ2
Ninjurin-2

2

1

High-throughput

0.606

High

1459947

YIPF1
Protein YIPF1

2

4

High-throughput

0.606

High

1244674

TMM65
Transmembrane protein 65

2

0

High-throughput

0.580

High

1449180

AAA1
Asc-type amino acid transporter 1

1

15

High-throughput

0.575

High

350423

ABHGA
Phosphatidylserine lipase ABHD16A

2

3

High-throughput

0.553

High

1109088

AQP6
Aquaporin-6

2

1

High-throughput

0.553

High

1382976

S2546
Mitochondrial outer membrane protein SLC25A46

2

1

High-throughput

0.553

High

1388818

YIPF6
Protein YIPF6

2

6

High-throughput

0.553

High

1389671

MFSD3
Major facilitator superfamily domain-containing protein 3

2

1

High-throughput

0.553

High

1414497

DERL1
Derlin-1

2

3

High-throughput

0.553

High

1429146

MFF
Mitochondrial fission factor

2

2

High-throughput

0.553

High

1434960

REEP4
Receptor expression-enhancing protein 4

2

2

High-throughput

0.553

High

1449025

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

2

7

High-throughput

0.553

High

1449814

TM14B
Transmembrane protein 14B

2

1

High-throughput

0.553

High

1459948

FLVC1
Choline/ethanolamine transporter FLVCR1

1

9

High-throughput

0.536

High

535649

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.515

High

650473

FGFR3
Fibroblast growth factor receptor 3

1

13

High-throughput

0.515

High

931150

HSP72
Heat shock-related 70 kDa protein 2

1

3

High-throughput

0.515

High

442516

GELS
Gelsolin

1

0

High-throughput

0.493

High

1329528

FITM2
Acyl-coenzyme A diphosphatase FITM2

1

1

High-throughput

0.489

High

1448038

PXMP2
Peroxisomal membrane protein 2

1

1

High-throughput

0.489

High

282634

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

5

High-throughput

0.470

High

1081572

Q0VDC6
peptidylprolyl isomerase

1

1

High-throughput

0.470

High

1430284

FXYD6
FXYD domain-containing ion transport regulator 6

1

0

High-throughput

0.460

High

338664

AGRL2
Adhesion G protein-coupled receptor L2

1

5

High-throughput

0.445

High

488885

FURIN
Furin

1

3

High-throughput

0.445

High

839514

PI4KA
Phosphatidylinositol 4-kinase alpha

1

3

High-throughput

0.445

High

1111742

STIM1
Stromal interaction molecule 1

1

2

High-throughput

0.445

High

1177204

MICB
MHC class I polypeptide-related sequence B

1

2

High-throughput

0.445

High

1295453

C2CD5
C2 domain-containing protein 5

1

1

High-throughput

0.445

High

1309812

IPRI
Inositol 1,4,5-trisphosphate receptor-interacting protein

1

1

High-throughput

0.445

High

1439038

GBA2
Non-lysosomal glucosylceramidase

1

2

High-throughput

0.445

High

1447608

ITM2C
Integral membrane protein 2C

1

2

High-throughput

0.445

High

506681

GPHRB
Golgi pH regulator B

1

6

High-throughput

0.437

High

903006

MMP15
Matrix metalloproteinase-15

1

0

High-throughput

0.426

High

942198

WNT4
Protein Wnt-4

1

0

High-throughput

0.426

High

1387012

ORAI1
Calcium release-activated calcium channel protein 1

1

0

High-throughput

0.426

High

1459945

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.426

High

85413

GPHRA
Golgi pH regulator A

1

6

High-throughput

0.407

High

184939

SPTC1
Serine palmitoyltransferase 1

1

2

High-throughput

0.407

High

185046

SPTC2
Serine palmitoyltransferase 2

1

2

High-throughput

0.407

High

186446

TM9S1
Transmembrane 9 superfamily member 1

1

7

High-throughput

0.407

High

187573

FANCA
Fanconi anemia group A protein

1

2

High-throughput

0.407

High

249271

MA1A2
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

1

2

High-throughput

0.407

High

250949

TPST1
Protein-tyrosine sulfotransferase 1

1

6

High-throughput

0.407

High

322170

GLCE
D-glucuronyl C5-epimerase

1

1

High-throughput

0.407

High

388677

C1QA
Complement C1q subcomponent subunit A

1

1

High-throughput

0.407

High

399746

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

1

1

High-throughput

0.407

High

1102289

ATM
Serine-protein kinase ATM

1

3

High-throughput

0.407

High

1179930

ALG11
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

1

2

High-throughput

0.407

High

1248309

CP20A
Cytochrome P450 20A1

1

2

High-throughput

0.407

High

1252846

NFXL1
NF-X1-type zinc finger protein NFXL1

1

6

High-throughput

0.407

High

1329327

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

1

5

High-throughput

0.407

High

1336783

SIA7C
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

1

3

High-throughput

0.407

High

1339473

TOIP2
Torsin-1A-interacting protein 2

1

1

High-throughput

0.407

High

1348355

GOGA5
Golgin subfamily A member 5

1

4

High-throughput

0.407

High

1352960

PO210
Nuclear pore membrane glycoprotein 210

1

2

High-throughput

0.407

High

1357959

DCAKD
Dephospho-CoA kinase domain-containing protein

1

2

High-throughput

0.407

High

1411655

ADPGK
ADP-dependent glucokinase

1

3

High-throughput

0.407

High

1412553

GCP2
Gamma-tubulin complex component 2

1

4

High-throughput

0.407

High

1421177

LNP
Endoplasmic reticulum junction formation protein lunapark

1

4

High-throughput

0.407

High

1439475

SEC12
Guanine nucleotide-exchange factor SEC12

1

5

High-throughput

0.407

High

1459946

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

2

High-throughput

0.407

High

328276

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

2

0

High-throughput

0.316

High

944427

SYJ2B
Synaptojanin-2-binding protein

2

0

High-throughput

0.316

High

1249533

SNORC
Protein SNORC

2

0

High-throughput

0.316

High

1413812

TM208
Transmembrane protein 208

2

0

High-throughput

0.316

High

1432048

TMM60
Transmembrane protein 60

2

0

High-throughput

0.316

High

248637

FADS1
Acyl-CoA

1

0

High-throughput

0.279

Low

70850

SYC1L
Synaptonemal complex central element protein 1-like

1

0

High-throughput

0.251

Low

342690

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.232

Low

1218497

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

0

High-throughput

0.232

Low

1410887

MGME1
Mitochondrial genome maintenance exonuclease 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025