HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001725 - stress fiber GO:0003779 - actin binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0015629 - actin cytoskeleton and 1 others more... GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2602 Hs			1 793
+	Hs
		261303 FLNB_HUMAN (1-2602): 0: 2855: 100.00		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		261212 FLNB_HUMAN (1-2602): 0: 2855: 100.00		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		148205 FLNB_HUMAN (1-2602): 0: 2855: 100.00		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		598077 FLNA_HUMAN (1-2602): 0: 2661: 69.59		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		598255 FLNA_HUMAN (1-2602): 0: 2661: 69.59		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		598391 FLNA_HUMAN (1-2602): 0: 2661: 69.59		MYO5A_HUMAN (42-632): 2.15e-24: 112: 15.29
+	Hs
		597987 FLNA_HUMAN (1-2602): 0: 2661: 69.59		MYH11_HUMAN (2-686): 1.62e-23: 109: 9.77
+	Hs
		597985 FLNA_HUMAN (1-2602): 0: 2661: 69.59		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		598129 FLNA_HUMAN (1-2602): 0: 2661: 69.59		PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94
+	Hs
		148392 FLNA_HUMAN (1-2602): 0: 2661: 69.59		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		598338 FLNA_HUMAN (1-2602): 0: 2661: 69.59		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Hs
		984582 FLNC_HUMAN (6-2602): 0: 1470: 35.38		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		148807 FLNC_HUMAN (6-2602): 0: 1470: 35.38		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		963299 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		521484 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		724781 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		148722 ACTN3_HUMAN (5-364): 1.21e-118: 402: 26.88		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		148339 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		148463 ACTN2_HUMAN (5-364): 2.6e-116: 395: 26.61		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		148690 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87