HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	18157088
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2602 Hs			1 548
+	Hs
		598307 FLNA_HUMAN (1-2602): 0: 2661: 69.59		TRI55_HUMAN (1-548): 6.44e-121: 368: 100.00
+	Hs
		261288 FLNB_HUMAN (1-2602): 0: 2855: 100.00		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		598309 FLNA_HUMAN (1-2602): 0: 2661: 69.59		TRIM6_HUMAN (13-420): 1.73e-74: 246: 13.13
+	Hs
		62677 FLNA_HUMAN (1-2602): 0: 2661: 69.59		TRI64_HUMAN (13-398): 3.94e-71: 236: 15.13
+	Hs
		598377 FLNA_HUMAN (1-2602): 0: 2661: 69.59		TRI33_HUMAN (25-531): 1.06e-65: 233: 10.86
+	Hs
		598187 FLNA_HUMAN (1-2602): 0: 2661: 69.59		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		1052933 FLNC_HUMAN (6-2602): 0: 1470: 35.38		TRI55_HUMAN (1-548): 6.44e-121: 368: 100.00
+	Hs
		1052919 FLNC_HUMAN (6-2602): 0: 1470: 35.38		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		1052932 FLNC_HUMAN (6-2602): 0: 1470: 35.38		TRI54_HUMAN (1-353): 3.29e-78: 252: 62.54
+	Hs
		211440 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		TRIM3_HUMAN (7-525): 5.4e-80: 267: 16.64
+	Hs
		521464 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		RO52_HUMAN (12-405): 3.8e-74: 245: 15.87
+	Hs
		211495 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		RO52_HUMAN (12-405): 3.8e-74: 245: 15.87
+	Hs
		521640 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		TRI33_HUMAN (25-531): 1.06e-65: 233: 10.86
+	Hs
		62673 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		TRI64_HUMAN (13-398): 3.94e-71: 236: 15.13
+	Hs
		211693 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		TRI33_HUMAN (25-531): 1.06e-65: 233: 10.86
+	Mm
		1186640 ACTN1_MOUSE (5-364): 6.66e-117: 397: 27.15		TRI59_MOUSE (17-301): 3.82e-65: 219: 23.08
+	Hs
		521567 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		963355 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		211603 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		1172280 MACF1_HUMAN (16-239): 9.3e-35: 149: 40.69		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39