HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: SIR7 (Q9NRC8)
NAD-dependent protein deacetylase sirtuin-7 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-7) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)
Gene: SIRT7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22586326
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 400
+	Hs
		598340 FLNA_HUMAN (1-2602): 0: 2661: 69.59		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		261296 FLNB_HUMAN (1-2602): 0: 2855: 100.00		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		598230 FLNA_HUMAN (1-2602): 0: 2661: 69.59		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		1052951 FLNC_HUMAN (6-2602): 0: 1470: 35.38		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		521624 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		963433 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		211673 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		521578 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		1344536 MACF1_HUMAN (16-239): 9.3e-35: 149: 40.69		SIR7_HUMAN (1-400): 0: 535: 100.00