HitPredict

Interactor 1: NCOR1 (O75376)
Nuclear receptor corepressor 1 (N-CoR) (N-CoR1)
Gene: NCOR1

Interactor 2: HDAC4 (P56524)
Histone deacetylase 4 (HD4) (EC 3.5.1.98)
Gene: HDAC4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 11804585, 10640275, 10860984, 27684187, 31040226, 23752268, 17956988
Identification Methods affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Hist_deacetyl~Myb_DNA-binding
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2440
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024