HitPredict

Interactor 1: TRIM3 (O75382)
Tripartite motif-containing protein 3 (EC 2.3.2.27) (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97)
Gene: TRIM3

Interactor 2: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	zf-B_box~zf-C3HC4
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 744 Hs			1 728
+	Hs
		585019 RO52_HUMAN (18-481): 1.33e-82: 272: 14.97		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252493 TRI39_HUMAN (14-452): 2.51e-76: 257: 17.84		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1115440 TRI60_HUMAN (15-426): 2.47e-70: 239: 16.51		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1149890 TRI68_HUMAN (14-493): 3.04e-68: 234: 14.12		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		536942 TRI27_HUMAN (9-478): 8.29e-67: 231: 15.26		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252460 TRI54_HUMAN (9-293): 5.88e-68: 229: 23.36		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1204896 TRI50_HUMAN (14-478): 1.79e-65: 227: 17.56		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		175698 TRI18_HUMAN (12-293): 2.93e-62: 222: 18.31		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		734704 TRI23_HUMAN (18-169): 3.18e-13: 75.1: 27.78		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00