HitPredict

Interactor 1: ULK1 (O75385)
Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)
Gene: ULK1

Interactor 2: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.902

The method score is based on:

Property Details
Experiments 25686248, 21795849, 21460634, 21460630
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HEAT~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0031267 - small GTPase binding
GO:0031669 - cellular response to nutrient levels
GO:0044877 - protein-containing complex binding
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1050
Hs

1 1335
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024