HitPredict

Interactor 1: DTNB (O60941)
Dystrobrevin beta (DTN-B) (Beta-dystrobrevin)
Gene: DTNB

Interactor 2: SNTG2 (Q9NY99)
Gamma-2-syntrophin (G2SYN) (Syntrophin-5) (SYN5)
Gene: SNTG2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.735

Property	Details
Experiments	32296183, 10747910, 28514442, 33961781, unassigned1304, 25416956
Identification Methods	two hybrid, pull down, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, mammalian protein protein interaction trap, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 627 Hs			1 539
+	Mm
		267255 DTNB_MOUSE (1-623): 0: 787: 93.11		SNTG2_MOUSE (1-539): 2.69e-160: 469: 83.12
+	Mm
		1365302 DTNA_MOUSE (1-626): 0: 708: 70.41		SNTG2_MOUSE (1-539): 2.69e-160: 469: 83.12
+	Hs
		262440 DTNB_HUMAN (1-627): 0: 795: 100.00		SNTG1_HUMAN (23-529): 3.33e-124: 375: 50.78
+	Mm
		267256 DTNB_MOUSE (1-623): 0: 787: 93.11		SNTG1_MOUSE (23-529): 4.51e-124: 375: 50.59
+	Hs
		262383 DTNB_HUMAN (1-627): 0: 795: 100.00		SNTB1_HUMAN (3-521): 2.92e-112: 345: 22.79
+	Hs
		262381 DTNB_HUMAN (1-627): 0: 795: 100.00		SNTB2_HUMAN (31-521): 1.08e-108: 336: 23.31
+	Mm
		267252 DTNB_MOUSE (1-623): 0: 787: 93.11		SNTB2_MOUSE (16-521): 6.51e-111: 341: 23.40
+	Mm
		267257 DTNB_MOUSE (1-623): 0: 787: 93.11		SNTB1_MOUSE (3-521): 3.65e-110: 340: 22.41
+	Hs
		262380 DTNB_HUMAN (1-627): 0: 795: 100.00		SNTA1_HUMAN (27-521): 3.6e-102: 318: 24.51
+	Mm
		267251 DTNB_MOUSE (1-623): 0: 787: 93.11		Q3UVD6_MOUSE (29-521): 2.78e-105: 326: 25.59
+	Mm
		1365304 DTNA_MOUSE (1-626): 0: 708: 70.41		SNTG1_MOUSE (23-529): 4.51e-124: 375: 50.59
+	Mm
		1222581 DTNA_MOUSE (1-626): 0: 708: 70.41		SNTB2_MOUSE (16-521): 6.51e-111: 341: 23.40
+	Mm
		1408812 DTNA_MOUSE (1-626): 0: 708: 70.41		SNTB1_MOUSE (3-521): 3.65e-110: 340: 22.41
+	Hs
		168599 DTNB_HUMAN (1-627): 0: 795: 100.00		CSKP_HUMAN (9-520): 4.11e-72: 249: 9.75
+	Mm
		1190950 DTNA_MOUSE (1-626): 0: 708: 70.41		Q3UVD6_MOUSE (29-521): 2.78e-105: 326: 25.59
+	Mm
		59514 DTNA_MOUSE (1-626): 0: 708: 70.41		A2AKD7_MOUSE (29-521): 1.77e-105: 326: 25.59
+	Mm
		1222576 DTNA_MOUSE (1-626): 0: 708: 70.41		SNTA1_MOUSE (29-521): 7.01e-105: 325: 25.59
+	Hs
		1104814 DTNA_HUMAN (1-626): 0: 692: 70.09		SNTA1_HUMAN (27-521): 3.6e-102: 318: 24.51
+	Hs
		168775 DTNA_HUMAN (1-626): 0: 692: 70.09		CSKP_HUMAN (9-520): 4.11e-72: 249: 9.75
+	Hs
		262433 DTNB_HUMAN (1-627): 0: 795: 100.00		LIN7B_HUMAN (58-154): 2.27e-33: 128: 36.08