HitPredict

Interactor 1: TULP3 (O75386)
Tubby-related protein 3 (Tubby-like protein 3)
Gene: TULP3

Interactor 2: IF122 (Q9HBG6)
Intraflagellar transport protein 122 homolog (WD repeat-containing protein 10) (WD repeat-containing protein 140)
Gene: IFT122

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

Property	Details
Experiments	28514442, 27173435, 33187986, 33961781, 27932497
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001843 - neural tube closure GO:0005929 - cilium GO:0045879 - negative regulation of smoothened signaling pathway GO:0061512 - protein localization to cilium
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 442 Hs			1 1241
+	Hs
		124527 TULP2_HUMAN (111-436): 1.74e-139: 411: 43.58		IF122_HUMAN (1-1241): 0: 1034: 100.00
+	Hs
		262611 TULP3_HUMAN (1-442): 0: 675: 100.00		WDR35_HUMAN (58-1098): 3.27e-152: 490: 15.71
+	Hs
		262552 TULP3_HUMAN (1-442): 0: 675: 100.00		IF140_HUMAN (15-1089): 1.39e-103: 361: 10.48
+	Hs
		124530 TULP2_HUMAN (111-436): 1.74e-139: 411: 43.58		WDR35_HUMAN (58-1098): 3.27e-152: 490: 15.71
+	Hs
		262514 TULP3_HUMAN (1-442): 0: 675: 100.00		WDR19_HUMAN (202-541): 3.71e-20: 99.4: 8.62
+	Hs
		124521 TULP2_HUMAN (111-436): 1.74e-139: 411: 43.58		IF140_HUMAN (15-1089): 1.39e-103: 361: 10.48
+	Hs
		124518 TULP2_HUMAN (111-436): 1.74e-139: 411: 43.58		WDR19_HUMAN (202-541): 3.71e-20: 99.4: 8.62