HitPredict

Interactor 1: SC22B (O75396)
Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)
Gene: SEC22B

Interactor 2: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.50	0.586

Property	Details
Experiments	24623722, 34079125, 32344865
Identification Methods	two hybrid, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 664
+	Mm
		139059 SC22B_MOUSE (1-215): 6.45e-91: 267: 100.00		LMNA_MOUSE (1-664): 1.23e-70: 243: 94.90
+	Dr
		71529 S22BB_DANRE (1-215): 1.71e-90: 266: 90.23		B3DKC5_DANRE (9-597): 8e-53: 194: 65.08
+	Dr
		71544 S22BA_DANRE (1-215): 1.62e-88: 261: 84.65		B3DKC5_DANRE (9-597): 8e-53: 194: 65.08
+	Hs
		263170 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37
+	Hs
		180785 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		360288 SC22A_HUMAN (1-143): 1.36e-46: 157: 40.82		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		180814 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37