HitPredict

Interactor 1: SC22B (O75396)
Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)
Gene: SEC22B

Interactor 2: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 1114
+	Hs
		180791 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		RET_HUMAN (1-1114): 0: 1295: 100.00
+	At
		85214 SC221_ARATH (1-214): 1.54e-78: 236: 46.30		PAM74_ARATH (227-1039): 1.43e-168: 521: 12.63
+	Hs
		263150 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61
+	Hs
		169152 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		MUSK_HUMAN (396-1018): 1.21e-135: 434: 25.28
+	Hs
		180799 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61
+	Hs
		180815 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89
+	Hs
		263183 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		FLT3_HUMAN (714-1014): 2.21e-72: 262: 40.00
+	Hs
		180876 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19