HitPredict

Interactor 1: SC22B (O75396)
Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)
Gene: SEC22B

Interactor 2: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Hs			1 192
+	Hs
		263218 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		263159 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		263359 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Hs
		263221 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		263210 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		263212 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		263146 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		850556 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		545275 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		850593 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Hs
		850548 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00
+	Hs
		850558 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		850550 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		850552 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		436215 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		564456 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49
+	Hs
		180804 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		180849 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00
+	Hs
		180793 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		180807 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49