Protein: BRAF
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf)

Gene: BRAF
Organism: Mus musculus
Interactions: 75
UniProt ID: P28028

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0002318 - myeloid progenitor cell differentiation
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004708 - MAP kinase kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

655980

RAF1
RAF proto-oncogene serine/threonine-protein kinase

4

18

Small-scale

0.873

High

655943

1433Z
14-3-3 protein zeta/delta

3

20

Small-scale

0.829

High

655931

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

2

20

Small-scale

0.775

High

655947

1433F
14-3-3 protein eta

2

20

Small-scale

0.775

High

655955

RASH
GTPase HRas

2

20

Small-scale

0.775

High

655957

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

2

20

Small-scale

0.775

High

655946

1433T
14-3-3 protein theta

2

20

Small-scale

0.757

High

93249

E9PWZ6
Myosin IXb

1

10

High-throughput

0.618

High

101497

F8VQ29
IQ motif containing GTPase activating protein 3

1

20

High-throughput

0.618

High

250867

1433S
14-3-3 protein sigma

1

20

High-throughput

0.618

High

384058

ARAF
Serine/threonine-protein kinase A-Raf

1

15

High-throughput

0.618

High

509467

CDK1
Cyclin-dependent kinase 1

1

11

High-throughput

0.618

High

655936

1433G
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]

1

20

High-throughput

0.618

High

655938

1433E
14-3-3 protein epsilon

1

15

High-throughput

0.618

High

655940

RAN
GTP-binding nuclear protein Ran

1

17

High-throughput

0.618

High

655948

CDK2
Cyclin-dependent kinase 2

1

20

High-throughput

0.618

High

655954

KSR1
Kinase suppressor of Ras 1

1

17

Small-scale

0.618

High

655958

MYOF
Myoferlin

1

5

High-throughput

0.618

High

655965

CPNE3
Copine-3

1

9

High-throughput

0.618

High

655966

DOCK1
Dedicator of cytokinesis protein 1

1

5

High-throughput

0.618

High

655973

SNX9
Sorting nexin-9

1

6

High-throughput

0.618

High

655977

RAP1B
Ras-related protein Rap-1b

1

20

High-throughput

0.618

High

655981

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.618

High

655985

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

15

High-throughput

0.618

High

655971

RAB38
Ras-related protein Rab-38

1

11

High-throughput

0.575

High

59959

A4FUW1
4932417H02Rik protein

1

16

High-throughput

0.479

High

93731

E9Q9B7
Kinase D-interacting substrate 220

1

12

High-throughput

0.479

High

192230

PHB2
Prohibitin-2

1

8

High-throughput

0.479

High

417785

G6PI
Glucose-6-phosphate isomerase

1

3

High-throughput

0.479

High

427714

ANXA2
Annexin A2

1

11

High-throughput

0.479

High

432406

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

435915

ENPL
Endoplasmin

1

20

High-throughput

0.479

High

444633

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

16

High-throughput

0.479

High

588704

BIP
Endoplasmic reticulum chaperone BiP

1

17

High-throughput

0.479

High

589613

VIME
Vimentin

1

7

High-throughput

0.479

High

627401

MCM3
DNA replication licensing factor MCM3

1

10

High-throughput

0.479

High

655932

GRP75
Stress-70 protein, mitochondrial

1

20

High-throughput

0.479

High

655933

ANXA5
Annexin A5

1

11

High-throughput

0.479

High

655935

IF5
Eukaryotic translation initiation factor 5

1

3

High-throughput

0.479

High

655937

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

13

High-throughput

0.479

High

655939

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

13

High-throughput

0.479

High

655941

HSP7C
Heat shock cognate 71 kDa protein

1

12

High-throughput

0.479

High

655942

DNJA1
DnaJ homolog subfamily A member 1

1

14

High-throughput

0.479

High

655944

PHB1
Prohibitin 1

1

8

High-throughput

0.479

High

655945

CSK2B
Casein kinase II subunit beta

1

6

High-throughput

0.479

High

655949

G3BP2
Ras GTPase-activating protein-binding protein 2

1

5

High-throughput

0.479

High

655950

PLD2
Phospholipase D2

1

2

High-throughput

0.479

High

655951

MSHR
Melanocyte-stimulating hormone receptor

1

1

High-throughput

0.479

High

655952

Q5SV02
RAD50 double strand break repair protein

1

18

High-throughput

0.479

High

655953

CDC37
Hsp90 co-chaperone Cdc37

1

11

High-throughput

0.479

High

655956

NPM
Nucleophosmin

1

5

High-throughput

0.479

High

655959

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

9

High-throughput

0.479

High

655960

ECM29
Proteasome adapter and scaffold protein ECM29

1

12

High-throughput

0.479

High

655961

FMNL3
Formin-like protein 3

1

7

High-throughput

0.479

High

655962

FACD2
Fanconi anemia group D2 protein homolog

1

4

High-throughput

0.479

High

655964

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

1

2

High-throughput

0.479

High

655967

WDR26
WD repeat-containing protein 26

1

12

High-throughput

0.479

High

655970

COPA
Coatomer subunit alpha

1

11

High-throughput

0.479

High

655974

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

3

High-throughput

0.479

High

655975

EED
Polycomb protein EED

1

11

High-throughput

0.479

High

655976

ATAD3
ATPase family AAA domain-containing protein 3

1

12

High-throughput

0.479

High

655978

DJB11
DnaJ homolog subfamily B member 11

1

14

High-throughput

0.479

High

655979

WDR6
tRNA

1

18

High-throughput

0.479

High

655982

PGAM1
Phosphoglycerate mutase 1

1

2

High-throughput

0.479

High

655983

AKAP8
A-kinase anchor protein 8

1

5

High-throughput

0.479

High

655984

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

17

High-throughput

0.479

High

655986

BAG3
BAG family molecular chaperone regulator 3

1

2

Small-scale

0.479

High

655968

GRAM4
GRAM domain-containing protein 4

1

0

High-throughput

0.458

High

655988

GNAS3
Neuroendocrine secretory protein 55

1

0

High-throughput

0.458

High

56979

A2A9M5
Dedicator of cytokinesis 7

1

5

High-throughput

0.437

High

655934

DHI2
11-beta-hydroxysteroid dehydrogenase type 2

1

5

High-throughput

0.437

High

655963

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

10

High-throughput

0.437

High

655969

Q8CHD7
MKIAA0678 protein

1

16

High-throughput

0.437

High

655972

SGPL1
Sphingosine-1-phosphate lyase 1

1

4

High-throughput

0.437

High

655987

DJB12
DnaJ homolog subfamily B member 12

1

18

High-throughput

0.437

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024