HitPredict

Interactor 1: SC22B (O75396)
Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)
Gene: SEC22B

Interactor 2: BET1L (Q9NYM9)
BET1-like protein (Golgi SNARE with a size of 15 kDa) (GOS-15) (GS15) (Vesicle transport protein GOS15)
Gene: BET1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005484 - SNAP receptor activity GO:0015031 - protein transport GO:0031201 - SNARE complex
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 111
+	Hs
		169333 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		BET1_HUMAN (2-106): 3.67e-36: 120: 31.43
+	Hs
		235130 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		STX10_HUMAN (7-91): 6.07e-25: 95.9: 12.94
+	Hs
		212690 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	Dm
		115845 M9PGI6_DROME (1-215): 2.77e-76: 230: 56.22		Q9VVX6_DROME (29-106): 1.21e-24: 91.6: 30.77
+	Hs
		169416 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		BET1_HUMAN (2-106): 3.67e-36: 120: 31.43
+	Sc
		605819 SEC22_YEAST (1-215): 1.97e-66: 205: 35.65		BET1_YEAST (1-105): 3.81e-26: 96.2: 16.19
+	Hs
		169321 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		BET1_HUMAN (2-106): 3.67e-36: 120: 31.43
+	Rn
		1125559 YKT6_RAT (30-188): 8.16e-53: 170: 23.13		BET1_RAT (2-106): 4.23e-36: 120: 31.43
+	Hs
		180946 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		BET1L_HUMAN (1-111): 7.13e-35: 117: 100.00
+	Mm
		193165 YKT6_MOUSE (30-188): 1.21e-52: 169: 23.13		BET1_MOUSE (2-106): 1.12e-35: 119: 31.43
+	Dm
		1178137 Q7JYX5_DROME (30-214): 7.52e-63: 196: 20.54		Q9VVX6_DROME (29-106): 1.21e-24: 91.6: 30.77
+	Rn
		192329 YKT6_RAT (30-188): 8.16e-53: 170: 23.13		BET1L_RAT (1-111): 5.79e-33: 112: 88.29
+	Hs
		212772 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	Hs
		180766 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	Sc
		611770 YKT6_YEAST (31-188): 1.64e-44: 148: 24.54		BET1_YEAST (1-105): 3.81e-26: 96.2: 16.19
+	Dm
		1374918 Q9W3M8_DROME (28-188): 3.61e-45: 150: 20.25		Q9VVX6_DROME (29-106): 1.21e-24: 91.6: 30.77