Protein: PUM3
Pumilio homolog 3 (HBV X-transactivated gene 5 protein) (HBV XAg-transactivated protein 5) (Minor histocompatibility antigen HA-8) (HLA-HA8)

Gene: PUM3
Organism: Homo sapiens
Interactions: 229
UniProt ID: Q15397

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005654 - nucleoplasm
GO:0005694 - chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

447052

NPM
Nucleophosmin

5

1

High-throughput

0.722

High

345860

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

4

8

High-throughput

0.694

High

978956

RS6
Small ribosomal subunit protein eS6

4

2

High-throughput

0.694

High

1148160

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

4

11

High-throughput

0.694

High

886494

CTCF
Transcriptional repressor CTCF

3

2

High-throughput

0.675

High

1148183

SRP68
Signal recognition particle subunit SRP68

3

1

High-throughput

0.675

High

969236

RS8
Small ribosomal subunit protein eS8

3

2

High-throughput

0.667

High

986054

RL8
Large ribosomal subunit protein uL2

3

1

High-throughput

0.667

High

1089413

ILF2
Interleukin enhancer-binding factor 2

3

4

High-throughput

0.667

High

1148115

ZCCHV
Zinc finger CCCH-type antiviral protein 1

3

3

High-throughput

0.667

High

1148120

ZC3H3
Zinc finger CCCH domain-containing protein 3

3

1

High-throughput

0.667

High

1148102

IF16
Gamma-interferon-inducible protein 16

3

2

High-throughput

0.656

High

372097

MYC
Myc proto-oncogene protein

3

3

High-throughput

0.640

High

898668

RL14
Large ribosomal subunit protein eL14

3

0

High-throughput

0.638

High

1148182

NOL12
Nucleolar protein 12

3

0

High-throughput

0.638

High

208263

RRP8
Ribosomal RNA-processing protein 8

2

1

High-throughput

0.628

High

228717

U3IP2
U3 small nucleolar RNA-interacting protein 2

2

6

High-throughput

0.628

High

301066

RL1D1
Ribosomal L1 domain-containing protein 1

2

4

High-throughput

0.628

High

521703

H14
Histone H1.4

2

5

High-throughput

0.628

High

785188

RL4
Large ribosomal subunit protein uL4

2

1

High-throughput

0.628

High

824163

RL13A
Large ribosomal subunit protein uL13

2

1

High-throughput

0.628

High

841368

RBM34
RNA-binding protein 34

2

15

High-throughput

0.628

High

855090

NOP2
28S rRNA

2

2

High-throughput

0.628

High

859294

RL5
Large ribosomal subunit protein uL18

2

1

High-throughput

0.628

High

959798

RS3A
Small ribosomal subunit protein eS1

2

2

High-throughput

0.628

High

960742

RL15
Large ribosomal subunit protein eL15

2

1

High-throughput

0.628

High

961737

RL37A
Large ribosomal subunit protein eL43

2

1

High-throughput

0.628

High

972419

RS14
Small ribosomal subunit protein uS11

2

2

High-throughput

0.628

High

975708

RL7A
Large ribosomal subunit protein eL8

2

4

High-throughput

0.628

High

977012

CNBP
CCHC-type zinc finger nucleic acid binding protein

2

3

High-throughput

0.628

High

978542

RL23A
Large ribosomal subunit protein uL23

2

2

High-throughput

0.628

High

1006420

SRPK2
SRSF protein kinase 2

2

6

High-throughput

0.628

High

1037162

H11
Histone H1.1

2

5

High-throughput

0.628

High

1037507

RL18A
Large ribosomal subunit protein eL20

2

1

High-throughput

0.628

High

1139915

RRS1
Ribosome biogenesis regulatory protein homolog

2

1

High-throughput

0.628

High

1148101

OASL
2'-5'-oligoadenylate synthase-like protein

2

2

High-throughput

0.628

High

1148110

RL7L
Ribosomal protein uL30-like

2

2

High-throughput

0.628

High

1148122

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

2

1

High-throughput

0.628

High

1148124

ZCHC7
Zinc finger CCHC domain-containing protein 7

2

7

High-throughput

0.628

High

1148128

PAPD5
Terminal nucleotidyltransferase 4B

2

4

High-throughput

0.628

High

1148130

BRX1
Ribosome biogenesis protein BRX1 homolog

2

7

High-throughput

0.628

High

1148148

EBP2
Probable rRNA-processing protein EBP2

2

1

High-throughput

0.628

High

1148150

MBB1A
Myb-binding protein 1A

2

1

High-throughput

0.628

High

1148156

RBM4
RNA-binding protein 4

2

12

High-throughput

0.628

High

1148159

MAK16
Protein MAK16 homolog

2

1

High-throughput

0.628

High

1148163

DDX31
ATP-dependent DNA helicase DDX31

2

8

High-throughput

0.628

High

1148167

SSF1
Suppressor of SWI4 1 homolog

2

3

High-throughput

0.628

High

1148174

RBM28
RNA-binding protein 28

2

12

High-throughput

0.628

High

1148176

NOP53
Ribosome biogenesis protein NOP53

2

2

High-throughput

0.628

High

1148177

H2AW
Core histone macro-H2A.2

2

2

High-throughput

0.628

High

182302

WDR46
WD repeat-containing protein 46

2

7

High-throughput

0.611

High

810117

RL3
Large ribosomal subunit protein uL3

2

1

High-throughput

0.611

High

1089674

ILF3
Interleukin enhancer-binding factor 3

2

9

High-throughput

0.611

High

1148193

RL26L
Ribosomal protein uL24-like

2

3

High-throughput

0.611

High

290570

SURF6
Surfeit locus protein 6

2

0

High-throughput

0.602

High

686177

RL13
Large ribosomal subunit protein eL13

2

0

High-throughput

0.602

High

716874

RL12
Large ribosomal subunit protein uL11

2

0

High-throughput

0.602

High

859841

RL28
Large ribosomal subunit protein eL28

2

0

High-throughput

0.602

High

984417

RL30
Large ribosomal subunit protein eL30

2

0

High-throughput

0.602

High

985474

RL32
Large ribosomal subunit protein eL32

2

0

High-throughput

0.602

High

1057756

RL18
Large ribosomal subunit protein eL18

2

0

High-throughput

0.602

High

1148104

KNOP1
Lysine-rich nucleolar protein 1

2

0

High-throughput

0.602

High

1148132

DGCR8
Microprocessor complex subunit DGCR8

2

0

High-throughput

0.602

High

1148153

ZNF2
Zinc finger protein 2

2

0

High-throughput

0.602

High

1148197

RL36
Large ribosomal subunit protein eL36

2

0

High-throughput

0.602

High

1148164

LN28A
Protein lin-28 homolog A

2

5

High-throughput

0.601

High

1148154

THAP7
THAP domain-containing protein 7

2

0

High-throughput

0.585

High

96687

E9PAV9
G patch domain-containing protein 4

2

2

High-throughput

0.584

High

649321

H1T
Histone H1t

2

5

High-throughput

0.574

High

935403

FGF8
Fibroblast growth factor 8

2

1

High-throughput

0.574

High

1148143

MAGBA
Melanoma-associated antigen B10

2

3

High-throughput

0.574

High

1148194

SRPK3
SRSF protein kinase 3

2

12

High-throughput

0.574

High

396168

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

1148168

ANLN
Anillin

2

0

High-throughput

0.559

High

74498

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

7

High-throughput

0.536

High

257864

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

2

High-throughput

0.536

High

286994

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

8

High-throughput

0.536

High

288654

NPM3
Nucleoplasmin-3

1

1

High-throughput

0.536

High

338844

CBX6
Chromobox protein homolog 6

1

2

High-throughput

0.536

High

428780

RLA0
Large ribosomal subunit protein uL10

1

4

High-throughput

0.536

High

595440

H15
Histone H1.5

1

5

High-throughput

0.536

High

595782

H13
Histone H1.3

1

5

High-throughput

0.536

High

596116

H12
Histone H1.2

1

5

High-throughput

0.536

High

634456

LMNB1
Lamin-B1

1

1

High-throughput

0.536

High

833118

MNDA
Myeloid cell nuclear differentiation antigen

1

2

High-throughput

0.536

High

961301

RL27
Large ribosomal subunit protein eL27

1

1

High-throughput

0.536

High

985180

RL10A
Large ribosomal subunit protein uL1

1

4

High-throughput

0.536

High

985677

RL11
Large ribosomal subunit protein uL5

1

2

High-throughput

0.536

High

1008739

RED1
Double-stranded RNA-specific editase 1

1

7

High-throughput

0.536

High

1016453

SRSF3
Serine/arginine-rich splicing factor 3

1

10

High-throughput

0.536

High

1027475

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

2

High-throughput

0.536

High

1060995

SRSF1
Serine/arginine-rich splicing factor 1

1

10

High-throughput

0.536

High

1099084

SRSF5
Serine/arginine-rich splicing factor 5

1

10

High-throughput

0.536

High

1099360

SRSF6
Serine/arginine-rich splicing factor 6

1

12

High-throughput

0.536

High

1112026

KRR1
KRR1 small subunit processome component homolog

1

2

High-throughput

0.536

High

1130743

RRP5
Protein RRP5 homolog

1

3

High-throughput

0.536

High

1148103

H2A2C
Histone H2A type 2-C

1

1

High-throughput

0.536

High

1148112

LN28B
Protein lin-28 homolog B

1

6

High-throughput

0.536

High

1148145

ZNF48
Zinc finger protein 48

1

1

High-throughput

0.536

High

1148146

SRPK1
SRSF protein kinase 1

1

5

High-throughput

0.536

High

1148149

RBM4B
RNA-binding protein 4B

1

12

High-throughput

0.536

High

1148161

GTPB4
GTP-binding protein 4

1

3

High-throughput

0.536

High

1148169

PRDM5
PR domain zinc finger protein 5

1

1

High-throughput

0.536

High

1148171

DDX21
Nucleolar RNA helicase 2

1

4

High-throughput

0.536

High

1148175

LYAR
Cell growth-regulating nucleolar protein

1

1

High-throughput

0.536

High

1148181

ZBT47
Zinc finger and BTB domain-containing protein 47

1

2

High-throughput

0.536

High

1148186

PURG
Purine-rich element-binding protein gamma

1

2

High-throughput

0.536

High

1148198

RBM19
Probable RNA-binding protein 19

1

14

High-throughput

0.536

High

611881

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

615804

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.513

High

788666

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

842384

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.513

High

854075

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

880311

RL34
Large ribosomal subunit protein eL34

1

0

High-throughput

0.513

High

1148108

HP1B3
Heterochromatin protein 1-binding protein 3

1

0

High-throughput

0.513

High

1148111

CC137
Coiled-coil domain-containing protein 137

1

0

High-throughput

0.513

High

1148116

LYRIC
Protein LYRIC

1

0

High-throughput

0.513

High

1148138

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

1148142

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.513

High

1148151

LLPH
Protein LLP homolog

1

0

High-throughput

0.513

High

1148152

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.513

High

1148162

REXO4
RNA exonuclease 4

1

0

High-throughput

0.513

High

1148189

ZN346
Zinc finger protein 346

1

0

High-throughput

0.513

High

1148192

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

191652

MAGB2
Melanoma-associated antigen B2

1

3

High-throughput

0.489

High

208842

ZBT24
Zinc finger and BTB domain-containing protein 24

1

2

High-throughput

0.489

High

517767

GLI4
Zinc finger protein GLI4

1

1

High-throughput

0.489

High

1148105

RN151
RING finger protein 151

1

1

High-throughput

0.489

High

1148117

PNM8A
Paraneoplastic antigen-like protein 8A

1

1

High-throughput

0.489

High

1148135

FGF13
Fibroblast growth factor 13

1

1

High-throughput

0.489

High

1148141

ZN668
Zinc finger protein 668

1

1

High-throughput

0.489

High

1148178

NHSL3
NHS-like protein 3

1

4

High-throughput

0.489

High

1148195

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

2

High-throughput

0.489

High

422141

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

129106

MEN1
Menin

1

1

High-throughput

0.479

High

140936

NOP56
Nucleolar protein 56

1

5

High-throughput

0.479

High

194207

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.479

High

241756

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

248299

HBP1
HMG box-containing protein 1

1

2

High-throughput

0.479

High

285299

EED
Polycomb protein EED

1

4

High-throughput

0.479

High

330992

KI20A
Kinesin-like protein KIF20A

1

3

High-throughput

0.479

High

385770

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.479

High

406209

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.479

High

588768

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

643858

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

3

High-throughput

0.479

High

695534

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

832526

ETV3
ETS translocation variant 3

1

1

High-throughput

0.479

High

872353

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

875672

PRC2A
Protein PRRC2A

1

5

High-throughput

0.479

High

899920

FXR1
RNA-binding protein FXR1

1

5

High-throughput

0.479

High

941169

IF6
Eukaryotic translation initiation factor 6

1

1

High-throughput

0.479

High

960123

RL26
Large ribosomal subunit protein uL24

1

3

High-throughput

0.479

High

984783

RL31
Large ribosomal subunit protein eL31

1

3

High-throughput

0.479

High

990257

1433Z
14-3-3 protein zeta/delta

1

7

High-throughput

0.479

High

998346

H31
Histone H3.1

1

6

High-throughput

0.479

High

1016885

H33
Histone H3.3

1

6

High-throughput

0.479

High

1035640

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.479

High

1040816

MECOM
Histone-lysine N-methyltransferase MECOM

1

1

High-throughput

0.479

High

1088361

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

2

High-throughput

0.479

High

1099922

TIF1B
Transcription intermediary factor 1-beta

1

3

High-throughput

0.479

High

1113172

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1126903

RBM39
RNA-binding protein 39

1

8

High-throughput

0.479

High

1132711

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

2

High-throughput

0.479

High

1148106

LARP7
La-related protein 7

1

12

High-throughput

0.479

High

1148107

HABP4
Intracellular hyaluronan-binding protein 4

1

1

High-throughput

0.479

High

1148121

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1148125

SIR6
NAD-dependent protein deacylase sirtuin-6

1

2

High-throughput

0.479

High

1148127

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1148131

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1148133

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1148134

KAT6A
Histone acetyltransferase KAT6A

1

2

High-throughput

0.479

High

1148147

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.479

High

1148155

DDX23
Probable ATP-dependent RNA helicase DDX23

1

4

High-throughput

0.479

High

1148158

FACD2
Fanconi anemia group D2 protein

1

3

High-throughput

0.479

High

1148172

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

2

High-throughput

0.479

High

1148173

NLE1
Notchless protein homolog 1

1

2

High-throughput

0.479

High

1148184

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

3

High-throughput

0.479

High

1148190

MED23
Mediator of RNA polymerase II transcription subunit 23

1

1

High-throughput

0.479

High

190920

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

223069

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

693757

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.458

High

768263

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

787024

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

0

High-throughput

0.458

High

982679

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

1148118

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1148129

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

1148137

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1148140

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1148166

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

0

High-throughput

0.458

High

1148179

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1148180

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.458

High

1148196

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

72776

B0UZZ8
WD repeat-containing protein 46

1

6

High-throughput

0.445

High

429936

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

1056743

FMR1
Fragile X messenger ribonucleoprotein 1

1

5

High-throughput

0.445

High

1130267

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

3

High-throughput

0.445

High

1148109

GPTC4
G patch domain-containing protein 4

1

2

High-throughput

0.445

High

1148165

CBX8
Chromobox protein homolog 8

1

2

High-throughput

0.445

High

1148187

DDX41
Probable ATP-dependent RNA helicase DDX41

1

4

High-throughput

0.445

High

1148119

HPS6
BLOC-2 complex member HPS6

1

0

High-throughput

0.438

High

411979

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

970551

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

1140313

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.437

High

1148113

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1148157

KLF16
Krueppel-like factor 16

1

1

High-throughput

0.437

High

1148191

HECD1
E3 ubiquitin-protein ligase HECTD1

1

2

High-throughput

0.437

High

983390

RS30
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein

1

0

High-throughput

0.426

High

886881

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.408

High

69946

A8KAG1
G patch domain-containing protein 4

1

2

High-throughput

0.407

High

376392

PDGFB
Platelet-derived growth factor subunit B

2

0

High-throughput

0.328

High

1148126

ZFP62
Zinc finger protein 62 homolog

2

0

High-throughput

0.328

High

1148136

CPNE4
Copine-4

2

0

High-throughput

0.328

High

1148170

ZNF71
Endothelial zinc finger protein induced by tumor necrosis factor alpha

2

0

High-throughput

0.328

High

1148139

PRR11
Proline-rich protein 11

2

0

High-throughput

0.318

High

1148188

ITBP2
Integrin beta-1-binding protein 2

1

0

High-throughput

0.282

High

137445

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

1

0

High-throughput

0.279

Low

657243

KALM
Anosmin-1

1

0

High-throughput

0.279

Low

1127388

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1148123

H18
Histone H1.8

1

0

High-throughput

0.279

Low

1148144

CC140
Coiled-coil domain-containing protein 140

1

0

High-throughput

0.279

Low

1148185

IL17B
Interleukin-17B

1

0

High-throughput

0.279

Low

1148199

MB212
Protein mab-21-like 2

1

0

High-throughput

0.279

Low

157413

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

226554

TLX2
T-cell leukemia homeobox protein 2

1

0

High-throughput

0.249

Low

272206

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.249

Low

400874

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.249

Low

408893

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.249

Low

720236

UFO
Tyrosine-protein kinase receptor UFO

1

0

High-throughput

0.249

Low

1148114

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025