HitPredict

Interactor 1: SC22B (O75396)
Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)
Gene: SEC22B

Interactor 2: SAR1B (Q9Y6B6)
Small COPII coat GTPase SAR1B (EC 3.6.5.2) (GTP-binding protein B) (GTBPB) (Secretion-associated Ras-related GTPase 1B)
Gene: SAR1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35844135
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0012507 - ER to Golgi transport vesicle membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 198
+	Hs
		263214 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		ARF6_HUMAN (21-196): 3.66e-74: 222: 30.11
+	Hs
		263369 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90
+	Sc
		594382 SEC22_YEAST (1-215): 1.97e-66: 205: 35.65		SAR1_YEAST (4-197): 1.73e-76: 229: 59.79
+	Hs
		850553 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		ARF6_HUMAN (21-196): 3.66e-74: 222: 30.11
+	Hs
		180854 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		ARF6_HUMAN (21-196): 3.66e-74: 222: 30.11
+	Sc
		503049 SEC22_YEAST (1-215): 1.97e-66: 205: 35.65		ARF1_YEAST (10-197): 2.45e-59: 185: 27.66
+	Hs
		263315 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		ARL11_HUMAN (22-191): 8.72e-25: 97.4: 33.33
+	Hs
		1294718 SC22A_HUMAN (1-143): 1.36e-46: 157: 40.82		SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90
+	Sc
		503075 YKT6_YEAST (31-188): 1.64e-44: 148: 24.54		ARF1_YEAST (10-197): 2.45e-59: 185: 27.66
+	Hs
		180899 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		ARL14_HUMAN (24-197): 1.44e-25: 99.4: 32.00