HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	38113892
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 183
+	Hs
		263559 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		UBE2A_HUMAN (4-150): 8.87e-65: 197: 30.46
+	Hs
		551657 DESP_HUMAN (419-952): 2.38e-60: 227: 12.98		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Hs
		1294888 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2D4_HUMAN (7-150): 2.75e-73: 218: 31.08
+	Hs
		919827 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73
+	Hs
		849411 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43
+	Hs
		895882 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05
+	Hs
		919860 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73
+	Hs
		849444 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43
+	Hs
		895910 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05
+	Hs
		125335 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73
+	Dm
		854579 SUDX_DROME (80-305): 6.98e-18: 91.4: 13.22		UBCD2_DROME (3-150): 2.35e-65: 202: 28.95
+	Hs
		125262 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43
+	Hs
		1282329 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2E3_HUMAN (5-150): 1.84e-65: 201: 28.00
+	Hs
		1294835 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2E2_HUMAN (5-150): 1.61e-65: 201: 27.33
+	Hs
		125300 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05
+	Hs
		851871 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33
+	Hs
		125629 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2E3_HUMAN (5-150): 1.84e-65: 201: 28.00
+	Hs
		125655 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2E2_HUMAN (5-150): 1.61e-65: 201: 27.33
+	Hs
		725129 MYH10_HUMAN (432-957): 1.68e-14: 80.8: 9.98		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Hs
		125263 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33