HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	15231748
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 158
+	Hs
		263559 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		UBE2A_HUMAN (1-154): 3.37e-67: 202: 41.56
+	Hs
		154776 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		1294888 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42
+	Hs
		849411 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12
+	Hs
		919827 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07
+	Hs
		895882 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2D3_HUMAN (4-157): 6.67e-73: 216: 35.07
+	Hs
		849444 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12
+	Hs
		919860 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07
+	Hs
		1294835 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2E2_HUMAN (3-156): 7.29e-69: 208: 33.77
+	Dm
		854579 SUDX_DROME (80-305): 6.98e-18: 91.4: 13.22		UBCD2_DROME (3-156): 2.21e-68: 208: 35.07
+	Hs
		1282329 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2E3_HUMAN (3-156): 2.14e-68: 207: 33.77
+	Hs
		125262 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12
+	Hs
		895910 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		UB2D3_HUMAN (4-157): 6.67e-73: 216: 35.07
+	Hs
		125335 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07
+	Hs
		851871 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2E1_HUMAN (3-156): 7.23e-67: 203: 33.12
+	Hs
		125300 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2D3_HUMAN (4-157): 6.67e-73: 216: 35.07
+	Hs
		125358 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		125655 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2E2_HUMAN (3-156): 7.29e-69: 208: 33.77
+	Hs
		125629 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2E3_HUMAN (3-156): 2.14e-68: 207: 33.77
+	Hs
		125263 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2E1_HUMAN (3-156): 7.23e-67: 203: 33.12