Protein: CCNA1
Cyclin-A1

Gene: CCNA1
Organism: Homo sapiens
Interactions: 86
UniProt ID: P78396

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

625350

CDK2
Cyclin-dependent kinase 2

20

20

Small-scale

0.986

High

804103

CDN1B
Cyclin-dependent kinase inhibitor 1B

8

15

Small-scale

0.968

High

758186

CDN1A
Cyclin-dependent kinase inhibitor 1

8

15

Small-scale

0.968

High

414855

CDK1
Cyclin-dependent kinase 1

4

20

Small-scale

0.882

High

590160

CCNA2
Cyclin-A2

3

5

High-throughput

0.861

High

943810

FZR1
Fizzy-related protein homolog

7

20

Small-scale

0.745

High

673266

WEE1
Wee1-like protein kinase

1

9

Small-scale

0.724

High

943783

SKP2
S-phase kinase-associated protein 2

4

3

Small-scale

0.696

High

943804

CDT1
DNA replication factor Cdt1

4

2

Small-scale

0.672

High

943780

CDC20
Cell division cycle protein 20 homolog

3

20

Small-scale

0.665

High

943775

H11
Histone H1.1

3

7

Small-scale

0.655

High

414240

RB
Retinoblastoma-associated protein

2

7

Small-scale

0.629

High

486888

MYBB
Myb-related protein B

2

2

Small-scale

0.629

High

943774

E2F1
Transcription factor E2F1

2

9

Small-scale

0.629

High

708417

MCM4
DNA replication licensing factor MCM4

2

3

Small-scale

0.619

High

822238

KC1D
Casein kinase I isoform delta

1

1

High-throughput

0.618

High

830329

KC1E
Casein kinase I isoform epsilon

1

4

High-throughput

0.618

High

943787

CUL1
Cullin-1

2

3

Small-scale

0.611

High

559062

H15
Histone H1.5

2

7

Small-scale

0.602

High

227146

PRKN
E3 ubiquitin-protein ligase parkin

2

3

Small-scale

0.601

High

673386

MPIP1
M-phase inducer phosphatase 1

2

8

Small-scale

0.584

High

847788

BRCA2
Breast cancer type 2 susceptibility protein

1

2

Small-scale

0.561

High

943779

INCA1
Protein INCA1

1

0

Small-scale

0.549

High

943781

GPS2
G protein pathway suppressor 2

1

0

Small-scale

0.549

High

943789

MCM6
DNA replication licensing factor MCM6

1

5

High-throughput

0.536

High

943792

CSN6
COP9 signalosome complex subunit 6

1

6

High-throughput

0.536

High

943799

CSN5
COP9 signalosome complex subunit 5

1

6

High-throughput

0.536

High

414485

PRGR
Progesterone receptor

1

0

Small-scale

0.529

High

943793

CCAR2
Cell cycle and apoptosis regulator protein 2

1

1

High-throughput

0.515

High

929399

RACK1
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.504

High

435039

SP1
Transcription factor Sp1

1

2

Small-scale

0.501

High

637674

PSA2
Proteasome subunit alpha type-2

1

2

Small-scale

0.501

High

650941

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

Small-scale

0.501

High

660112

RBL1
Retinoblastoma-like protein 1

1

7

Small-scale

0.501

High

706795

CKS2
Cyclin-dependent kinases regulatory subunit 2

1

20

Small-scale

0.501

High

764622

CUX1
Homeobox protein cut-like 1

1

2

Small-scale

0.501

High

895411

CKS1
Cyclin-dependent kinases regulatory subunit 1

1

20

Small-scale

0.501

High

943777

RBL2
Retinoblastoma-like protein 2

1

7

Small-scale

0.501

High

943800

H2B1A
Histone H2B type 1-A

1

1

Small-scale

0.501

High

943808

APC4
Anaphase-promoting complex subunit 4

1

2

Small-scale

0.501

High

200170

TGFI1
Transforming growth factor beta-1-induced transcript 1 protein

1

0

High-throughput

0.493

High

617514

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.493

High

522904

SRC
Proto-oncogene tyrosine-protein kinase Src

1

1

Small-scale

0.481

High

523663

XRCC6
X-ray repair cross-complementing protein 6

1

1

Small-scale

0.481

High

943803

RBM4
RNA-binding protein 4

1

1

Small-scale

0.481

High

943788

NPAT
Protein NPAT

1

0

Small-scale

0.480

High

124834

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

6

High-throughput

0.479

High

271069

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

2

Small-scale

0.479

High

627236

MCM3
DNA replication licensing factor MCM3

1

5

High-throughput

0.479

High

716985

CTNB1
Catenin beta-1

1

5

Small-scale

0.479

High

827330

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.479

High

832363

MCM2
DNA replication licensing factor MCM2

1

4

High-throughput

0.479

High

905830

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

8

High-throughput

0.479

High

915161

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

6

High-throughput

0.479

High

943776

FAK1
Focal adhesion kinase 1

1

3

High-throughput

0.479

High

943778

EP300
Histone acetyltransferase p300

1

6

Small-scale

0.479

High

943782

TIF1B
Transcription intermediary factor 1-beta

1

5

High-throughput

0.479

High

943784

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

2

High-throughput

0.479

High

943791

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

5

High-throughput

0.479

High

943798

LAR4B
La-related protein 4B

1

2

High-throughput

0.479

High

943805

XPO5
Exportin-5

1

4

High-throughput

0.479

High

943811

EXO1
Exonuclease 1

1

6

Small-scale

0.479

High

943812

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

1

Small-scale

0.479

High

166417

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.458

High

378515

OAT
Ornithine aminotransferase, mitochondrial

1

0

High-throughput

0.458

High

513989

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

0

High-throughput

0.458

High

606406

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.458

High

652811

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

771904

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

789737

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

857102

CAZA1
F-actin-capping protein subunit alpha-1

1

0

High-throughput

0.458

High

862373

ACLY
ATP-citrate synthase

1

0

High-throughput

0.458

High

878170

SEC13
Protein SEC13 homolog

1

0

High-throughput

0.458

High

943797

ATX2L
Ataxin-2-like protein

1

0

High-throughput

0.458

High

943801

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

943802

THIC
Acetyl-CoA acetyltransferase, cytosolic

1

0

High-throughput

0.458

High

943807

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.458

High

943796

MIPT3
TRAF3-interacting protein 1

1

2

High-throughput

0.457

High

943785

ORC1
Origin recognition complex subunit 1

1

7

Small-scale

0.445

High

943786

ORC2
Origin recognition complex subunit 2

1

3

Small-scale

0.445

High

943809

STML2
Stomatin-like protein 2, mitochondrial

1

2

High-throughput

0.437

High

943794

PRCA1
Protein PROCA1

1

0

Small-scale

0.275

Low

943806

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

0

High-throughput

0.269

Low

943795

KLDC9
Kelch domain-containing protein 9

1

0

Small-scale

0.251

Low

337224

AATM
Aspartate aminotransferase, mitochondrial

1

0

High-throughput

0.249

Low

943790

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024