HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: CPSF7 (Q8N684)
Cleavage and polyadenylation specificity factor subunit 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Cleavage factor Im complex 59 kDa subunit) (CFIm59) (Pre-mRNA cleavage factor Im 59 kDa subunit)
Gene: CPSF7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 471
+	Hs
		263650 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51
+	Hs
		808771 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		CPSF7_HUMAN (1-456): 1.39e-122: 367: 100.00
+	Hs
		269254 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		CPSF7_HUMAN (1-456): 1.39e-122: 367: 100.00
+	Hs
		1235773 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		CPSF7_HUMAN (1-456): 1.39e-122: 367: 100.00
+	Hs
		1235798 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		CPSF7_HUMAN (1-456): 1.39e-122: 367: 100.00
+	Hs
		125581 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		CPSF7_HUMAN (1-456): 1.39e-122: 367: 100.00
+	Hs
		154818 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51
+	Hs
		808655 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51
+	Hs
		1084649 ITSN2_HUMAN (41-720): 9.42e-36: 149: 9.78		CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51
+	Hs
		269244 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51
+	Hs
		1084573 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51
+	Hs
		1084614 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51
+	Hs
		125492 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51
+	Hs
		808925 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		PABP3_HUMAN (83-184): 4.77e-13: 73.4: 19.61
+	Hs
		516402 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		PABP1_HUMAN (73-165): 7.95e-10: 63: 19.36
+	Hs
		269201 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		PABP1_HUMAN (73-165): 7.95e-10: 63: 19.36
+	Sc
		376704 PRP40_YEAST (144-667): 4.38e-18: 91.1: 16.90		PABP_YEAST (83-159): 2.45e-16: 83.4: 24.68
+	Hs
		516643 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		PABP1_HUMAN (73-165): 7.95e-10: 63: 19.36
+	Hs
		125430 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		PABP4_HUMAN (73-165): 2.96e-11: 67.6: 18.28
+	Hs
		125122 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		PABP1_HUMAN (73-165): 7.95e-10: 63: 19.36