Protein: CHK1
Serine/threonine-protein kinase grp (EC 2.7.11.1) (Chk1 homolog) (Protein grapes)

Gene: CHK1, grp
Organism: Drosophila melanogaster
Interactions: 49
UniProt ID: O61661

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

263720

CHK1
Serine/threonine-protein kinase grp

1

18

Small-scale

0.647

High

263753

S6KL
Serine/threonine-protein kinase S6KL

1

16

High-throughput

0.590

High

263730

Q7K2L7
GH27120p

1

18

High-throughput

0.587

High

263742

CEG1A
Centaurin-gamma-1A

1

1

High-throughput

0.587

High

263731

Q7KNM2
Dorsal interacting protein 4

1

3

High-throughput

0.508

High

263741

ENA
Protein enabled

1

1

High-throughput

0.508

High

263743

Q9VFQ3
E5

1

2

High-throughput

0.508

High

263745

Q9VL21
LD11652p

1

2

High-throughput

0.508

High

263762

MED15
Mediator of RNA polymerase II transcription subunit 15

1

1

High-throughput

0.508

High

263722

O96989
CDC45L

1

1

Small-scale

0.501

High

84282

DIMM
Protein dimmed

1

0

High-throughput

0.486

High

263724

PCNA
Proliferating cell nuclear antigen

1

4

High-throughput

0.481

High

263727

Q0KHU0
Myosin 10A, isoform D

1

8

High-throughput

0.481

High

263733

Q7KRS7
Hephaestus, isoform G

1

6

High-throughput

0.481

High

263736

PANG2
Protein pangolin, isoform J

1

1

High-throughput

0.481

High

263759

Q9W1H7
Putative homeodomain protein

1

2

High-throughput

0.481

High

263723

RLA1
Large ribosomal subunit protein P1

1

1

High-throughput

0.464

High

263750

RG68F
Rho GTPase-activating protein 68F

1

3

High-throughput

0.464

High

263751

ODR4
Protein odr-4 homolog

1

2

High-throughput

0.464

High

263752

Q9VVY2
Uncharacterized protein

1

1

High-throughput

0.464

High

263760

Q9W221
MIP04282p

1

1

High-throughput

0.464

High

263748

Q9VQ95
Testis EndoG-Like 3

1

0

High-throughput

0.460

High

263721

O76136
Homeodomain protein

1

1

High-throughput

0.457

High

263729

RAD51
DNA repair protein Rad51 homolog

1

1

High-throughput

0.457

High

263740

Q8T0H5
LD03185p

1

6

High-throughput

0.457

High

263757

Q9VZ45
Myosin 10A, isoform C

1

8

High-throughput

0.457

High

263761

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.457

High

6

A0A021WW64
Uncharacterized protein, isoform G

1

1

High-throughput

0.439

High

95614

E3CTS2
MIP27658p

1

1

High-throughput

0.439

High

263734

Q7Z2C5
Uncharacterized protein

1

1

High-throughput

0.439

High

263725

PANG1
Protein pangolin, isoforms A/H/I/S

1

1

High-throughput

0.417

High

263735

Q868I9
PCNA

1

4

High-throughput

0.417

High

263738

Q8SYH8
RE57644p

1

1

High-throughput

0.417

High

263739

Q8SYU4
RE33778p

1

1

High-throughput

0.417

High

263747

Q9VN49
Smallish, isoform I

1

2

High-throughput

0.417

High

263756

Q9VYF9
RE28286p

1

1

High-throughput

0.417

High

263732

RS15B
Small ribosomal subunit protein uS8B

1

1

High-throughput

0.407

High

56703

A1ZAH1
FI05611p

1

0

High-throughput

0.265

Low

263726

HIL
Hillarin

1

0

High-throughput

0.265

Low

263737

Q8SXG9
RE65335p

1

0

High-throughput

0.265

Low

263746

Q9VL27
Alpha-galactosidase

1

0

High-throughput

0.265

Low

263754

Q9VY14
Uncharacterized protein

1

0

High-throughput

0.265

Low

263755

Q9VYA4
Ribonuclease H2 subunit B

1

0

High-throughput

0.265

Low

263758

Q9VZG2
Cuticular protein 64Aa

1

0

High-throughput

0.265

Low

53295

A1Z7M3
Notopleural, isoform A

1

0

High-throughput

0.251

Low

263728

Y3427
Uncharacterized protein CG43427

1

0

High-throughput

0.251

Low

263744

Q9VJ59
PRA1 family protein

1

0

High-throughput

0.249

Low

263749

Q9VSU9
GH27208p

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025